The Point Institute

Dr. Guilliams had a Great Conversation with Dr. Jaclyn Smeaton- on the Dutch Podcast a while back and it just went live. We talk about the HPA axis beyond the Stress response- which is critical to understand if you want to leverage the HPA axis in Chronic Disease Management. Take a listen and give your feedback below.

Season 3, Episode 10 - DUTCH Test Did you know the HPA axis manages all body systems and functions like an emergency response vehicle when stressors occur? Or that early life stressors can have permanent effects on the HPA axis? Hear this and more on today’s episode of the DUTCH Podcast. In this episode, host Jaclyn Smeaton, ND, a...

Take a listen to this Podcast that Dr. Guilliams did with Rupa Health. All about the Endothelial Glycocalyx and new research looking at how it can influence how your evaluated risk for Cardiometabolic Disease- and More.

The Frontiers of Endothelial Glycocalyx and Cardiovascular Health with Dr. Tom Guilliams In today's episode with Dr. Tom Guilliams, you’ll hear us take a deep dive on: 1. The secrets of the endothelial glycocalyx 2. Potential biomarkers for assessing glycocalyx activity 3. The role of glycocalyx in cardiovascular health 4. Lifestyle factors that support endothelial health 5. Insights ...

If you haven't been keeping up with the research showing the importance of the Endothelial Glycocalyx- especially related to Cardiometabolic Health- this excellent open access review paper is worth the time to read. https://www.frontiersin.org/articles/10.3389/fcvm.2022.897087/full

Check out Dr. Guilliams' Podcast interview with Patti and Michael on The Lab Report. He talks about his most recent book (Second Ed. of the Supporting Immune Function) and a range of other immune related topics.

Supporting Immune Function with Dr. Tom Guilliams - The Lab Report Podcast If there’s one thing we’ve all come to appreciate during the COVID-19 pandemic, it is the importance of a healthy immune system. The immune system is a complex network of various cells, proteins, and organs that work together to help your body recognize and mitigate potential invaders, as well a...

We are delighted to finally get a few copies of our Supplementing Dietary Nutrient Road map (First Edition) that were translated and published in Korean. The cover looks great, but beyond the few English words throughout, we are going to assume the translation was done correctly. The first of many translation projects, we hope.

Had a blast doing this podcast with Michael and Patti- fast-paced and lots of interesting questions. Can't wait to get back on with them and cover more of the "behind the scenes" issues that effect the selection of supplemental nutrients.

NEW PODCAST DROPPED!

Debunking Supplement Myths with Dr. Tom Guilliams Part 1

Patti & Michael ask the supplement guru your most burning questions

www.gdx.net/the-lab-report
The Point Institute

After 24 years as an employee of Ortho Molecular Products, today I (Dr. Guilliams) move into a new venture of my career. While I am still engaged with Ortho as a consultant (Senior Scientific Advisor), I will be exploring new opportunities to expand my writing, teaching and impact in the natural products, dietary supplement, nutrition and functional/integrative medicine communities. I want to thank my colleagues at Ortho Molecular Products for over 2 decades of support- which continues under this new venture; as well as the support of many others in the broader communities that I have been blessed to serve these past 24 years. I want to especially thank my team(s) over the past many years for helping me in so many countless ways.

We are delighted to announce that we just went to the printer (in Stevens Point!) to see the printing of our newest book. Here is Dr. Guilliams with Lindsey and Brianna (the primary research assistants for the project) holding up a sheet of printed covers for the greatly expanded and updated Second Edition of our first Roadmap- Supplementing Dietary Nutrients. We will be adding this book to our online Book store soon (print and eBook versions), and sending discount coupons to those of you who purchased the first edition. We will keep you posted.

One of Dr. Guilliams' career goals was to be able to co-write an important piece with his friend and mentor Jorn Dyerberg (a pioneer of omega-3 research). Their co-written chapter has just been published in a newly released textbook (Personalized and Precision Integrative Cardiovascular Medicine)- edited by Mark Houston. Many thanks to Jorn, Mark and the publisher Wolters Kluwer

Over the past year Dr. Guilliams has been exploring and lecturing on circadian rhythms; especially focusing on how stress and nutrients alter circadian genetic expression. Here is a study showing how the number and timing of meals helps maintain metabolic rhythms (spoiler alert- three meals per day is a pretty good standard). Beyond this paper, there is emerging data suggesting that time-restricted feeding (with their extended times of fasting for 12 hours or more), really help to switch on and off the cycles that manage circadian-related metabolic control. Our view is that times of eating should correspond with daylight hours, that this window should expand in the summer and shorten during the winter, and that skipping breakfast is not an ideal way to maintain a shorter eating window. More on this in future posts.

New diet that matches biological clock may be better for diabetes New research suggests that a three meals per day — and not a six meals per day — approach brings more benefits to people with type 2 diabetes.

Perhaps some of you saw this recent report showing that children considered to be high-risk for autism who were born to women who had been consuming prenatal vitamins early in their pregnancy had less than half the incidence of autism compared to those born to women not taking prenatal supplements.

They word their findings this way: In this cohort study of 241 younger siblings of children with autism, the prevalence of autism spectrum disorder was 14.1% in children whose mothers took prenatal vitamins in the first month of pregnancy compared with 32.7% in children whose mothers did not take prenatal vitamins during that time.

Statistically, they attribute much of this effect to the higher amounts of folate/folic acid and iron in prenatal supplements, as these differences were not seen in subject whose mothers consumed generic multivitamins (i.e., non-prenatal multivitamins).

Beyond the most obvious take-away: that taking a prenatal supplement before and during pregnancy is great insurance for a range of issues; perhaps including reducing the risk for ASD, there is something more at play here. These data reveal that many people are likely closer to the threshold of nutrient deficiency (or at least functional insufficiency) than they think. Outside of the vulnerability of fetal development in genetically-susceptible individuals (which accentuated these subtle deficiencies in this study), insufficient nutrient status is likely behind a myriad of metabolic inefficiencies, many of which remain below clinical detectability. How many other conditions, especially in genetically-vulnerable individuals, are likely to be linked with long-term insufficiency in a particular nutrient or group of nutrients for which supplementation might be a simple solution?

Prenatal Vitamins May Help Decrease Autism Risk in Infants A new study found that women who took prenatal vitamins even before they conceived appeared to have less chance of having their child develop autism.

While it may seem a bit too good to be true, a recent study suggests that Type 2 diabetics may benefit greatly from taking 500 mg of vitamin C, twice a day. While this study was small, it showed that subjects taking vitamin C had a 36% reduction in their glucose levels after a meal (compared to subject not taking the vitamin C) and nearly 3 hours less hyperglycemia during a single day.

We will be digging into this a bit more, and comparing it to other published data on the role of vitamin C supplementation and glucose/insulin effects; but this is something that is safe to recommend to any type 2 diabetic and easy to implement. Linus Pauling would not be surprised!

Vitamin C linked to reduced glucose levels in type 2 diabetes Vitamin C supplementation is associated with improved blood glucose levels in people with type 2 diabetes, research suggests. A small Australian study, published in the journal Diabetes, Obesity and Metabolism, reports that people with type 2 diabetes who took a vitamin C tablet two times a day redu...