JAMA Neurology

Self-reported seizure durations in a large outpatient sample were often longer than laboratory-recorded values, with 90% of seizures lasting ≤4 minutes and substantial variation by seizure type and age group in . https://ja.ma/4oojuOO

Integrating genetic and pathological data increased diagnostic accuracy and identified ancestry-related differences in , supporting biologically informed diagnostic tools and future pathology-targeted therapeutic trials.

https://ja.ma/4aj6J20

A reperfusion-guided systolic blood pressure strategy improved functional outcomes and reduced hemorrhagic transformation for patients with acute after endovascular therapy compared with guideline-recommended management. https://ja.ma/4aoaJhJ

Among patients with acute ischemic due to large-vessel occlusion, standard-dose tenecteplase resulted in greater early reperfusion vs low-dose , with comparable functional and safety outcomes.

https://ja.ma/4aDfpjQ

Integrating genetic and pathological data increased diagnostic accuracy and identified ancestry-related differences in , supporting biologically informed diagnostic tools and future pathology-targeted therapeutic trials. https://ja.ma/4vwIpSi

Performance of the FDA-cleared Lumipulse plasma for amyloid pathology detection in varied by site and reagent lots, highlighting need for local assay verification and ongoing quality control.

https://ja.ma/4ajg5L9

An unusual congenital fusion of the left and right oculomotor nerves was identified in a child with complex and ptosis, demonstrating a rare variant of cranial nerve dysgenesis on neuroimaging.

https://ja.ma/4unsBjY

A patient with cavin-4 IgG-positive immune-mediated rippling muscle disease achieved complete clinical and serological remission following B-cell-targeted therapy with rituximab.

Complete Remission of Cavin-4 Immunoglobulin G Rippling Muscle Disease After Rituximab Therapy This case report describes a 65-year-old man who experienced complete remission of cavin-4 immunoglobulin G (IgG) rippling muscle disease after receiving rituximab therapy.

Peripheral neuropathy involves nerve damage that can cause numbness, tingling, pain, and mild muscle weakness in the legs and, sometimes, the arms.

📄 This JAMA Patient Page describes common symptoms, diagnosis, and treatment of peripheral neuropathy.

https://ja.ma/4e4cd1F

Among patients with acute ischemic due to large-vessel occlusion, standard-dose tenecteplase resulted in greater early reperfusion vs low-dose , with comparable functional and safety outcomes.

https://ja.ma/4dPMnzF