Cortex Neurology

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https://n.neurology.org/content/early/2023/07/21/WNL.0000000000207505

Lecanemab: Looking Before We Leap Lecanemab, a novel amyloid-sequestering agent, recently received accelerated FDA approval for the treatment of mild Dementia due to Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI). Approval was based on a large Phase 3 trial, Clarity, which demonstrated reductions in amyloid plaque burden...

https://n.neurology.org/content/early/2023/07/26/WNL.0000000000207757

Antiamyloid Monoclonal Antibody Therapy for Alzheimer Disease: Emerging Issues in Neurology With recent data demonstrating that lecanemab treatment can slow cognitive and functional decline in early symptomatic Alzheimer disease (AD), it is widely anticipated that this drug and potentially other monoclonal antibody infusions targeting amyloid-β protein will imminently be realistic options...

https://www.alz.org/alzheimers-dementia/treatments/lecanemab-leqembi

Lecanemab Approved for Treatment of Early Alzheimer's Disease Lecanemab (Leqembi™) has received accelerated approval as a treatment for early Alzheimer’s from the U.S. Food and Drug Administration.

Explainer: Who is eligible for the new FDA-approved Alzheimer's drug? The U.S. Food and Drug Administration on Thursday granted standard approval to Eisai and Biogen's Leqembi for patients with Alzheimer's disease.

https://www.statnews.com/2023/06/16/the-fda-needs-a-risk-evaluation-and-mitigation-strategy-for-alzheimers-drug-lecanemab/

The FDA needs a risk evaluation and mitigation strategy for Alzheimer's drug lecanemab The problem with the new Alzheimer’s drugs isn’t the drugs.

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