AGLab

One of our best lead compounds: L-NPDNJ😉

Frontiers | N-nonyloxypentyl-L-deoxynojirimycin reduces Stenotrophomonas maltophilia virulence in vitro and in Galleria mellonella infection model IntroductionStenotrophomonas maltophilia is an opportunistic pathogen able to resist multiple classes of antibiotics and form robust biofilms, making it diff...

proud and happy...our last paper!😉

L-NBDNJ allosteric chaperone for multiple defective enzymes involved in lysosomal storage disorders (LSDs)
https://www.sciencedirect.com/science/article/pii/S004520682600489X?via%3Dihub

Benvenuta Sole, l'AGLab ti stava aspettando. Brava Anna Esposito il tuo miglior risultato di sempre! Ovviamente senza nulla togliere a Luigi Moreno

from my sweet and passionate students, thank you Natalia, Claudia & Michela for this beautiful thought!

To Cure a Rose Foundation | Imagine To Cure a Rose Foundation is creating treatments for children with rare genetic diseases, like Rose. Thank you to Horizon Therapeutics for supporting our mis...

Iminosugars may help advance treatments for Sanfilippo: Cell study... Treatment with sugary molecules called iminosugars can reduce the toxic buildup of heparan sulfate in cell models of Sanfilippo, a study says.

Just published :-))

N-Substituted l-Iminosugars for the Treatment of Sanfilippo Type B Syndrome Sanfilippo syndrome comprises a group of four genetic diseases due to the lack or decreased activity of enzymes involved in heparan sulfate (HS) catabolism. HS accumulation in lysosomes and other cellular compartments results in tissue and organ dysfunctions, leading to a wide range of clinical symp...

Our last article is on the cover of EurJOC!

Congratulation to Anna Esposito who won an european competition for a two years post-doc fellowship granted by ECFS/CFE.
Ad maiora always😉

The most determined and resilient students of the Organic Chemistry course (year 2022) of the Degree Course in Chemical Engineering. See you soon and good luck😉