Fishhead Labs LLC

Pathology Wednesday!

Photomicrograph of the skin of a rainbow trout using AFB stain to show high numbers of macrophages expanded by acid-fast rods (arrow). 4X magnification

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Histology Wednesday!
Photomicrograph of the lung showing an intravascular fibrin thrombus with leukocytes (arrow). H&E, 20X magnification.

Pathology Wednesday!
Photomicrograph of the kidney of a Bufo Toad showing duct with squamous metaplasia (arrow). H&E, 20X magnification.

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Fungal Wednesday!

Photomicrograph of the granulomatous stomach lesion showing abundant fungal organisms (arrow). H&E, 40X magnification.

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Holiday Pathology!

Some tumors are stranger than fiction...

This ovarian mass from a dog was diagnosed as a teratoma, an interesting but benign tumor that develops from germ cells capable of differentiating into tissues from multiple embryonic germ layers.

Under the microscope (and even grossly), this tumor contained an incredible assortment of tissues, including:

Cartilage 🦴
Neuroparenchyma (brain tissue) 🧠
Epithelial acini
Haired skin
And a large cyst packed with keratin and hair!

Teratomas are fascinating because they can contain mature, well-differentiated tissues that have no business being in the o***y. It's essentially a biological grab bag, with skin, nervous tissue, bone, cartilage, muscle, glands, and even teeth occasionally making an appearance.

Cases like this are a reminder of just how extraordinary biology can be.

Worms!
Photomicrograph of the intestine of a Silver Hatchet fish showing intraluminal, male and female Camallanus nematodes. Wet mount, 4x magnification

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Pathology Wednesday!
Photomicrograph of the skin of a tortoise showing hyperplastic epidermis and thick hyperkeratosis (arrow). H&E, 4X magnification.

Wet-mount Wednesday!
Necrotic gills of a pompano with high numbers of Trophonts (marine velvet). Wet mount, 4X magnification

Pathology Wednesday!
Photomicrograph of the skin of a waterdog showing erosion and loss of the epidermis (arrow). H&E, 4X magnification.

Pathology Wednesday!
Photomicrograph of the foot of an Axolotl showing ulceration of the skin and a thick mat of water mold and bacteria adhered to and invading the dermis (arrow). H&E, 10X magnification.