Genetic Engineering & Biotechnology News

Updated Amplification Tool Rapidly Detects Mycoplasma

This nucleic acid amplification technique detects 180 mycoplasma species at single-copy sensitivity for biologics testing.

Yeasen Biotechnology Offical, Xi’an Jiaotong - Liverpool University Affiliated School

Updated Amplification Tool Rapidly Detects Mycoplasma This nucleic acid amplification technique detects 180 mycoplasma species at single-copy sensitivity for biologics testing.

Gorilla Adenovirus Brings Natural Edge to Cancer Therapy

Angelo Raggioli, PhD, head of technology development at ReiThera Srl, describes a platform built on a gorilla adenovirus that was discovered, not designed. ReiThera’s gorilla-derived adenovirus platform combines innate tumor selectivity, low seroprevalence, and systemic-delivery advantages.

Gorilla Adenovirus Brings Natural Edge to Cancer Therapy ReiThera’s gorilla-derived adenovirus platform combines innate tumor selectivity, low seroprevalence, and systemic-delivery advantages.

The Confidence Gap: Why Drug Discovery’s Data Explosion Hasn’t Solved Its Billion-Dollar Decision Problem

In this June issue Thought Leader article Laurence Arnold, PhD, head of R&D at Pelago Bioscience, discusses prioritizing proof over progress, so decision-makers can fail faster–and smarter. Many failures were avoidable earlier. Hard-working teams just didn't have data that would let them make the call with confidence when it mattered most, before massive resources were committed.

The Confidence Gap: Why Drug Discovery’s Data Explosion Hasn’t Solved Its Billion-Dollar Decision Problem Yet despite this explosion in capability, our industry's most fundamental challenge remains stubbornly intact.

Fighting Antimicrobial Resistance with Biomaterials and Phages

Antimicrobial resistance (AMR) is a significant global health threat, with its impact felt across all regions of the world.

Harvard Medical School

Fighting Antimicrobial Resistance with Biomaterials and Phages Antimicrobial resistance (AMR) is a significant global health threat, with its impact felt across all regions of the world.

Measuring Direct, Bystander, and Off-Target ADC Killing with the HiBiT TCK Platform

Promega’s nonlytic, bioluminescent bioassay platform that distinguishes bystander from direct cytotoxicity in a single co-culture experiment.

Measuring Direct, Bystander, and Off-Target ADC Killing with the HiBiT TCK Platform Promega’s nonlytic, bioluminescent bioassay platform that distinguishes bystander from direct cytotoxicity in a single co-culture experiment.

New mRNA Delivery Platform Restores Muscle Function in DMD Models

Engineered extracellular vesicles that deliver full-length DMD mRNA to skeletal muscle restored dystrophin production and significantly improved muscle strength and function in Duchenne muscular dystrophy models without notable toxicity.

UT MD Anderson Cancer Center

New mRNA Delivery Platform Restores Muscle Function in DMD Models Engineered extracellular vesicles delivering full-length DMD mRNA restored dystrophin and improved muscle strength and function in DMD models.

Don't Miss Out! Practical Strategies for AAV Capsid Characterization

Tue, June 16, 2026 10:00 AM - 11:00 AM CDT

In this GEN webinar, the second of a three-part series on AAVs, experts from USP Biologics and Bio-Techne will share practical analytical tools that support optimal AAV capsid characterization and explore how the USP’s AAV8 reference standards supports robust full and empty capsid analysis. The session will highlight how AAV full/empty reference materials can be used to evaluate method performance, compare technologies, and gain confidence in product-defining ratios.

Register for this FREE webinar series sponsored by U.S. Pharmacopeia: https://hubs.li/Q04jFkVz0

mRNA Tails Play Key Role in Folding Regulatory Proteins

A new Memorial Sloan Kettering Cancer Center study shows that highly conserved mRNA 3' UTRs facilitate the folding of intrinsically disordered proteins. “What we show is that for thousands of regulatory proteins in human cells, the genetic code alone isn’t enough to make a functional protein—you need the RNA chaperone too,” said Christine Mayr, MD, PhD, a member of the Sloan Kettering Institute.

mRNA Tails Play Key Role in Folding Regulatory Proteins A new MSK study shows that highly conserved mRNA 3' UTRs facilitate the folding of intrinsically disordered proteins.

Don't Miss This New eBook! From Discovery to GMP: Building Scalable Cell Therapy Manufacturing

This eBook brings together perspectives from Genetic Engineering & Biotechnology News and ElevateBio to examine both the technical and operational realities shaping cell therapy today.

Download this free eBook sponsored by ElevateBio: https://hubs.li/Q04fTVHf0

Origins of First Eukaryotes Linked to Contributions from Multiple Bacteria and Giant Viruses

The Institute for Research in Biomedicine (IRB Barcelona) team used the computing power of the MareNostrum series of supercomputers to analyze public genomic data spanning biodiversity as a whole.

Origins of First Eukaryotes Linked to Contributions from Multiple Bacteria and Giant Viruses The team used the computing power of the MareNostrum series of supercomputers to analyze public genomic data spanning biodiversity as a whole.