The Wellness Way - Jupiter
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10/02/2026
Leucovorin went from headlines to a lot of confusion. 𧬠Folate needs a receptor to reach the brain, and some autistic kids have antibodies that may block it. Small trials showed improvements in language, especially in kids with those antibodies. But the largest trial was retracted in 2026, and the FDA approved leucovorin only for rare genetic cerebral folate deficiency, not autism.
š„ On dairy: one small 2008 study found antibody levels dropped on a milk-free diet and rose again when milk was reintroduced.
Promising, but it measured antibodies, not symptoms. If you go dairy-free, replace calcium and vitamin D.
š„ On inflammation: these antibodies are an immune response, and research suggests inflammatory markers run modestly higher in autism on average. Sleep, gut comfort, whole foods, and treating infections are low-risk ways to support the immune system.
š The research:āØā¢ 2013 (Molecular Psychiatry): In 93 autistic kids at a specialty clinic, about 75% of those tested had folate receptor antibodies
2018 (Molecular Psychiatry): A 12-week trial of 48 kids found leucovorin improved verbal communication vs placebo, most in kids with the antibodies.
āØā¢ 2008 (Dev Med Child Neurol): In 33 kids with cerebral folate deficiency, antibody levels dropped on a milk-free diet and rose again when milk returned.
āØā¢ 2026 (Molecular Psychiatry): A review of 98 studies found inflammatory markers modestly higher in autism on average, though the evidence was mostly weak.
āØā¢ 2024 (Biomed Pharmacother): One study found lower antibody levels in autistic boys than in other boys, a reminder that results donāt all agree.
Promising for some, not proven. Talks to your provider, and check B12 first.
Education, not medical advice.
āØ
š When a child is struggling with behavior, sometimes thereās more to understand beneath the surface.
Every child is different, and thatās why I believe we have to look at the whole pictureānot just one symptom.
š¬ Testing can give us additional information about areas like gut health, nutrition, and neurotransmitter metabolism that may help guide a more individualized approach.
The goal isnāt to blame one lab marker or assume weāve found the answer.
Itās about gathering the right information, putting the pieces together, and using that information to better support the child in front of us.
š§© Not one marker. Not one magic answer. Just more information.
Comment TEST below to learn more about our testing approach, or click the link in our bio to schedule a complimentary call.
THIS IS NOT MEDICAL ADVICE. PLEASE CONTACT YOUR PHYSICIAN OR QUALIFIED HEALTHCARE PROFESSIONAL FOR PERSONALIZED MEDICAL GUIDANCE.
š Gut symptoms can sometimes give us clues that arenāt obvious from the outside.
When a child is dealing with digestive issues, picky eating, communication challenges, or changes in behavior, looking at the gut can give us additional information about what may be happening internally.
š¬ Testing can help us look at different pieces of the puzzleāfrom the gut microbiome to yeast, bacterial balance, and intestinal immune activity.
The goal isnāt to blame one marker or assume weāve found the answer.
Itās about gathering the right information and putting it together with the childās history and symptoms.
š§© Not one marker. Not one magic answer. Just more information to help us better understand where a child may need support.
Comment TEST below to learn more about our testing approach, or click the link in our bio to schedule a complimentary call.
THIS IS NOT MEDICAL ADVICE. PLEASE CONTACT YOUR PHYSICIAN OR QUALIFIED HEALTHCARE PROFESSIONAL FOR PERSONALIZED MEDICAL GUIDANCE.
Picky eating in autism isnāt a parenting failure. š½ļø Research suggests autistic kids are about 5x more likely to have feeding challenges, often tied to sensory sensitivity. A narrow diet can mean less protein, calcium, and other nutrients the body uses for sleep, mood, and energy. No pressure, lots of safety, and bring it up with your provider or a feeding therapist. Education, not medical advice.
Sources//
Sharp et al., J Autism Dev Disord, 2013 ā meta-analysis, 17 studies; OR ā 5.1 for feeding problems; lower calcium (OR 0.31) and protein (OR 0.35). https://link.springer.com/article/10.1007/s10803-013-1771-5
Scurvy case series, 3 autistic children with refusal to walk, gingivitis; authors recommend multivitamin when selectivity is high. Pediatric Neurology, 2019. https://pubmed.ncbi.nlm.nih.gov/30795887/
Sensory ā food selectivity: Cermak et al., J Am Diet Assoc, 2010 (VERIFY before citing on screen).
š The gut is more than just digestion.
Your childās gut is closely connected to their immune system, microbiome, digestion, and overall health.
š¬ This is one reason I like using testing strategically. The right test can give us additional information about things like bacterial balance, digestive function, gut immune defenses, and other patterns that may be easy to miss from symptoms alone.
But testing isnāt about finding one abnormal number and blaming it for everything.
Itās about putting the pieces together.
š§© Not one marker. Not one magic answer. Just more information to help us better understand the individual child and make more informed decisions about how to support them.
Every child is different, which is why there isnāt one test or one approach that works the same way for everyone.
Comment TEST below to learn more about our testing approach, or click the link in our bio to schedule a complimentary call.
THIS IS NOT MEDICAL ADVICE. PLEASE CONTACT YOUR PHYSICIAN OR QUALIFIED HEALTHCARE PROFESSIONAL FOR PERSONALIZED MEDICAL GUIDANCE.
Sleep struggles in autism are common, and research suggests physiology plays a real role. š Melatonin starts with the protein we digest. Serotonin is mostly made in the gut, and itās about regulation, not just ālowā levels. Iron only counts if itās absorbed. Start with the body, build the routine, and work with your provider on supplements.
Education, not medical advice.
A small caveat: Most of this research is small or observational. It shows links, not causes. Itās one piece of the puzzle, not a diagnosis or a treatment plan, and every child is different. Talk with your provider before starting supplements, especially iron.
Rossignol & Frye, 2011, review and meta-analysis.
Gringras et al., JAACAP, 2017
Yano et al., Cell, 2015
Gabriele et al., 2014, meta-analysis of 22 studies.
Marler et al., J Autism Dev Disord, 2016
Dosman et al., Pediatric Neurology, 2007
Iron absorption physiology
Mazurek & Sohl, 2016
Cohen et al., JAMA, 2023
š Sometimes the symptoms we see on the outside are only part of the story.
When a child is struggling with behavior, digestion, focus, sleep, or nutrition, I want to understand the bigger pictureānot just focus on one symptom.
š¬ Testing can give us additional clues about the gut environment, digestion, nutrient needs, and metabolic pathways that may help guide a more individualized support plan.
The goal isnāt to chase one abnormal marker.
Itās to put the pieces together.
š§© Not one marker. Not one magic answer. Just more information to help us better understand the individual child.
If youād like to learn more about our testing approach, comment TEST below or click the link in our bio to schedule a complimentary call.
THIS IS NOT MEDICAL ADVICE. PLEASE CONTACT YOUR PHYSICIAN OR QUALIFIED HEALTHCARE PROFESSIONAL FOR PERSONALIZED MEDICAL GUIDANCE.
š When a child is struggling with constipation, I donāt want to only focus on getting them to have a bowel movement.
I want to understand the bigger picture.
How often are they going?
What does the stool look like?
Are they bloated?
Are they uncomfortable?
How is their diet?
And what might be happening within their gut environment?
š§© The digestive system is complex, and there isnāt always one simple explanation for why a child is struggling.
Thatās why I believe in taking the time to understand the individual child instead of automatically giving every child the same recommendations.
š¬ Sometimes testing can provide additional information that helps us ask better questions and make more individualized decisions about support.
Every child deserves an approach that considers their history, their symptoms, and their unique needs.
Comment TEST below if youād like to learn more about our testing approach.
THIS IS NOT MEDICAL ADVICE. PLEASE CONTACT YOUR PHYSICIAN OR QUALIFIED HEALTHCARE PROFESSIONAL FOR PERSONALIZED MEDICAL GUIDANCE.
š Severe constipation doesnāt always mean a child simply needs more fiber.
This little girl was eating a good diet and getting plenty of fiber, but was still struggling with constipation severe enough to require an ER visit.
Her testing gave us additional clues about her gut environment, including yeast findings and short-chain fatty acids.
š¬ The goal isnāt to blame one marker. Itās to look at the whole pictureāhistory, symptoms, diet, and testingāto guide a more individualized approach.
Every child is different. š
Comment TEST to learn more about our testing approach.
THIS IS NOT MEDICAL ADVICE. PLEASE CONTACT YOUR PHYSICIAN OR QUALIFIED HEALTHCARE PROFESSIONAL FOR MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT.
š Sometimes a behavior can tell us something a child canāt fully explain with words.
š¬ His testing gave us additional information about digestion, pancreatic enzyme output, short-chain fatty acids, gut bacteria, and cellular metabolism.
The goal wasnāt to look at one abnormal marker and assume we had the answer.
It was about putting the pieces together and asking
Sometimes, the little things children do are telling us something. We just have to pay attention. š
Comment TEST below if youād like to learn more about our testing approach, or click the link in our bio to schedule a complimentary call.
THIS IS NOT MEDICAL ADVICE. PLEASE CONTACT YOUR PHYSICIAN OR QUALIFIED HEALTHCARE PROFESSIONAL FOR MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT.
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