Alpha2EQ by Creative Science
The only product to functionally isolate the a2M molecule from the horse's blood to help target inflammation in joints, soft tissues & airways.
💉 One draw. Multiple uses. Zero drugs.
✔ Multiple doses for injections or nebulization
✔ Freezable up to 12 months for future use
✔ No risk of banned substances
Alpha2EQ™ is the only product designed to isolate the a*m molecule from your horse’s blood.
Ask your veterinarian about Alpha2EQ™ as an alternative to steroids for inflammation in joints, soft tissues, and airways.
🔗 Learn more: alpha2eq.com
*m
04/02/2026
We get asked all the time:
“How much is it?” and “Is it available here?"🌍🐎
Alpha2EQ® is already being used on horses around the world, including:
• United States
• Canada
• Mexico
• South America
• European Union
• United Kingdom
• Ireland
• Middle East
• Hong Kong
• Australia
• New Zealand
• South Africa
Pricing can vary by region. Because Alpha2EQ® is provided through veterinarians, individual clinics determine their own pricing.
We recommend contacting your veterinarian for the most accurate pricing.
💬Let us know in the comments where in the world you've used Alpha2EQ!🌎
Nebulizing Alpha2EQ® is a key part of Dr. Kristina Eisaman’s approach to reducing upper airway inflammation, helping young horses breathe more comfortably and keeping them on track for success.
When Alpha2EQ® is nebulized, alpha-2 macroglobulin (A*M) is delivered directly into the airway—helping your horse’s body to remove inflammation at the source.
📊Pilot Study Highlights (34 horses, 6 U.S. sites):
✔️ 88.2% success rate (30/34 horses improved significantly)
✔️ 100% showed improved weighted clinical scores
✔️ 94.1% improved by >30%
⏳ Duration of response
Many horses maintained reduced clinical signs for up to 6 months after the initial loading dose series
🔁 Ongoing support
For most horses exposed to ongoing irritants, one nebulization per month has helped keep the inflammation manageable
Alpha2EQ® is redefining how veterinarians support equine asthma and respiratory health.
03/14/2026
When inflammation becomes significant — from injury, wear-and-tear, or degenerative conditions — your horse’s natural A*M levels may not be enough to keep up.
That’s where Alpha2EQ™ comes in.
By isolating and concentrating functional A*M from the blood, Alpha2EQ™ allows veterinarians to deliver this powerful molecule exactly where it’s needed most — whether that’s joints, soft tissues, the respiratory system (via nebulization), or even the eye in cases like Equine Recurrent Uveitis (ERU).
💬 Where have you used Alpha2EQ™ for inflammation in your horses?
👇Drop a photo of your horse with your comment so we can see who we've helped!
*M
🐴 Lexington, KY veterinarian Dr. Kriss Eisaman of Equine Medical Associates shares why Alpha2EQ® is her go-to for managing joint inflammation in older racehorses.
A smarter way to support joint health and help keep horses doing what they love. 💙
Ask your vet about Alpha2EQ®
02/28/2026
𝐖𝐡𝐲 𝐕𝐞𝐭𝐞𝐫𝐢𝐧𝐚𝐫𝐢𝐚𝐧𝐬 𝐂𝐡𝐨𝐨𝐬𝐞 𝐀𝐥𝐩𝐡𝐚𝟐𝐄𝐐™
𝐓𝐚𝐫𝐠𝐞𝐭𝐞𝐝 𝐈𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐢𝐨𝐧 𝐂𝐨𝐧𝐭𝐫𝐨𝐥
Alpha2EQ™ addresses inflammation at its source by using functional A*M to bind and remove destructive proteases and cytokines—helping break the inflammatory cycle that can lead to further damage.
𝐍𝐚𝐭𝐮𝐫𝐚𝐥 & 𝐃𝐫𝐮𝐠-𝐅𝐫𝐞𝐞
Processed from the horse’s own blood, Alpha2EQ™ is a drug-free therapy with no risk of banned substances—making it suitable for competition horses.
𝐏𝐫𝐨𝐯𝐞𝐧 𝐕𝐞𝐫𝐬𝐚𝐭𝐢𝐥𝐢𝐭𝐲
Alpha2EQ™ supports a wide range of inflammatory conditions, including:
✔ Osteoarthritis
✔ Tendon & ligament injuries
✔ Heaves, asthma & COPD
✔ Kissing spines
✔ Sacroiliac (SI) dysfunction
✔ Laminitis
✔ Equine Recurrent Uveitis
𝐄𝐚𝐬𝐲 𝐒𝐭𝐚𝐥𝐥-𝐒𝐢𝐝𝐞 𝐔𝐬𝐞
The AlphaActive™ process allows for quick, stall-side preparation, enabling veterinarians to deliver targeted therapy on site during farm visits.
02/20/2026
🫁 Dust. Pollen. Seasonal irritants.
They don’t just affect comfort — they affect performance.
By nebulizing Alpha2EQ™, A*M is delivered directly to the airway, helping reduce inflammation where it starts and support easier breathing.
Ask your veterinarian about Alpha2EQ™ nebulization. 💙
*M
02/11/2026
Joint inflammation and cartilage stress begin far earlier than most owners realize — especially in performance horses. From tight turns, high speed, and fast stops to repetitive impact, young athletes are at risk for a lot of inflammation.
Alpha2EQ™ may help:
🔹 Protect joint degeneration in young horses
🔹 Reduce joint inflammation from stressors such as heavy training or futurity seasons
🔹 Help keep them comfortable to keep performing at their best
Inflammation is always easier to manage in the early stages, and we want longevity with our equine partners!
Do you have to pick between steroids and Alpha2EQ™? Not always!
Depending on the case, some veterinarians use:
✨ Steroids for quick relief to mask clinical signs
✨ Alpha2EQ™ for long-term care and precise support after diagnosis
One blocks inflammation temporarily.
One removes the inflammatory mediators causing the damage, with no known risks of long term or repetitive use.
Every case is different— and sometimes different tools work beautifully together, especially when addressing multiple joints, large-volume areas, or respiratory inflammation.
*M
01/30/2026
✨At the core of Alpha2EQ™ is functionally isolated A*M, a powerful, naturally occurring protein found in every horse's bloodstream.
But here’s the challenge…
When a horse faces injury, excessive inflammation, or degenerative changes, their natural A*M levels are not enough to keep up with the inflammation. That’s where Alpha2EQ™ can help make the difference.
Using our patented AlphaActive™ filtration process, we isolate and concentrate this molecule—creating a targeted therapy that can be delivered directly where your horse needs it most:
✔️ Joints
✔️ Soft tissues
✔️ Airway (via nebulization)
✔️ Even eyes in cases like Equine Recurrent Uveitis (ERU)
Whether your horse is a high-level athlete, a trail partner, or a beloved retiree, Alpha2EQ™ can help support healing by reducing the inflammatory mediators.
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77024