Alpha2EQ by Creative Science
The only product to functionally isolate the a2M molecule from the horse's blood to help target inflammation in joints, soft tissues & airways.
๐ One draw. Multiple uses. Zero drugs.
โ Multiple doses for injections or nebulization
โ Freezable up to 12 months for future use
โ No risk of banned substances
Alpha2EQโข is the only product designed to isolate the a*m molecule from your horseโs blood.
Ask your veterinarian about Alpha2EQโข as an alternative to steroids for inflammation in joints, soft tissues, and airways.
๐ Learn more: alpha2eq.com
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04/02/2026
We get asked all the time:
โHow much is it?โ and โIs it available here?"๐๐
Alpha2EQยฎ is already being used on horses around the world, including:
โข United States
โข Canada
โข Mexico
โข South America
โข European Union
โข United Kingdom
โข Ireland
โข Middle East
โข Hong Kong
โข Australia
โข New Zealand
โข South Africa
Pricing can vary by region. Because Alpha2EQยฎ is provided through veterinarians, individual clinics determine their own pricing.
We recommend contacting your veterinarian for the most accurate pricing.
๐ฌLet us know in the comments where in the world you've used Alpha2EQ!๐
Nebulizing Alpha2EQยฎ is a key part of Dr. Kristina Eisamanโs approach to reducing upper airway inflammation, helping young horses breathe more comfortably and keeping them on track for success.
When Alpha2EQยฎ is nebulized, alpha-2 macroglobulin (A*M) is delivered directly into the airwayโhelping your horseโs body to remove inflammation at the source.
๐Pilot Study Highlights (34 horses, 6 U.S. sites):
โ๏ธ 88.2% success rate (30/34 horses improved significantly)
โ๏ธ 100% showed improved weighted clinical scores
โ๏ธ 94.1% improved by >30%
โณ Duration of response
Many horses maintained reduced clinical signs for up to 6 months after the initial loading dose series
๐ Ongoing support
For most horses exposed to ongoing irritants, one nebulization per month has helped keep the inflammation manageable
Alpha2EQยฎ is redefining how veterinarians support equine asthma and respiratory health.
03/14/2026
When inflammation becomes significant โ from injury, wear-and-tear, or degenerative conditions โ your horseโs natural A*M levels may not be enough to keep up.
Thatโs where Alpha2EQโข comes in.
By isolating and concentrating functional A*M from the blood, Alpha2EQโข allows veterinarians to deliver this powerful molecule exactly where itโs needed most โ whether thatโs joints, soft tissues, the respiratory system (via nebulization), or even the eye in cases like Equine Recurrent Uveitis (ERU).
๐ฌ Where have you used Alpha2EQโข for inflammation in your horses?
๐Drop a photo of your horse with your comment so we can see who we've helped!
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๐ด Lexington, KY veterinarian Dr. Kriss Eisaman of Equine Medical Associates shares why Alpha2EQยฎ is her go-to for managing joint inflammation in older racehorses.
A smarter way to support joint health and help keep horses doing what they love. ๐
Ask your vet about Alpha2EQยฎ
02/28/2026
๐๐ก๐ฒ ๐๐๐ญ๐๐ซ๐ข๐ง๐๐ซ๐ข๐๐ง๐ฌ ๐๐ก๐จ๐จ๐ฌ๐ ๐๐ฅ๐ฉ๐ก๐๐๐๐โข
๐๐๐ซ๐ ๐๐ญ๐๐ ๐๐ง๐๐ฅ๐๐ฆ๐ฆ๐๐ญ๐ข๐จ๐ง ๐๐จ๐ง๐ญ๐ซ๐จ๐ฅ
Alpha2EQโข addresses inflammation at its source by using functional A*M to bind and remove destructive proteases and cytokinesโhelping break the inflammatory cycle that can lead to further damage.
๐๐๐ญ๐ฎ๐ซ๐๐ฅ & ๐๐ซ๐ฎ๐ -๐
๐ซ๐๐
Processed from the horseโs own blood, Alpha2EQโข is a drug-free therapy with no risk of banned substancesโmaking it suitable for competition horses.
๐๐ซ๐จ๐ฏ๐๐ง ๐๐๐ซ๐ฌ๐๐ญ๐ข๐ฅ๐ข๐ญ๐ฒ
Alpha2EQโข supports a wide range of inflammatory conditions, including:
โ Osteoarthritis
โ Tendon & ligament injuries
โ Heaves, asthma & COPD
โ Kissing spines
โ Sacroiliac (SI) dysfunction
โ Laminitis
โ Equine Recurrent Uveitis
๐๐๐ฌ๐ฒ ๐๐ญ๐๐ฅ๐ฅ-๐๐ข๐๐ ๐๐ฌ๐
The AlphaActiveโข process allows for quick, stall-side preparation, enabling veterinarians to deliver targeted therapy on site during farm visits.
02/20/2026
๐ซ Dust. Pollen. Seasonal irritants.
They donโt just affect comfort โ they affect performance.
By nebulizing Alpha2EQโข, A*M is delivered directly to the airway, helping reduce inflammation where it starts and support easier breathing.
Ask your veterinarian about Alpha2EQโข nebulization. ๐
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02/11/2026
Joint inflammation and cartilage stress begin far earlier than most owners realize โ especially in performance horses. From tight turns, high speed, and fast stops to repetitive impact, young athletes are at risk for a lot of inflammation.
Alpha2EQโข may help:
๐น Protect joint degeneration in young horses
๐น Reduce joint inflammation from stressors such as heavy training or futurity seasons
๐น Help keep them comfortable to keep performing at their best
Inflammation is always easier to manage in the early stages, and we want longevity with our equine partners!
Do you have to pick between steroids and Alpha2EQโข? Not always!
Depending on the case, some veterinarians use:
โจ Steroids for quick relief to mask clinical signs
โจ Alpha2EQโข for long-term care and precise support after diagnosis
One blocks inflammation temporarily.
One removes the inflammatory mediators causing the damage, with no known risks of long term or repetitive use.
Every case is differentโ and sometimes different tools work beautifully together, especially when addressing multiple joints, large-volume areas, or respiratory inflammation.
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