Betterhumans Inc.

Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity - GeroScience Claims surrounding exceptional longevity are sometimes disputed or dismissed for lack of credible evidence. Here, we present three DNA methylation-based age estimators (epigenetic clocks) for verifying age claims of centenarians. The three centenarian clocks were developed based on n = 7039 bloo...

We just got an Illumina MiniSeq DNA/RNA sequencer in today. Along with two Illumina iScan beadchip readers (which we use for measuring DNA methylation for Horvath Clocks), and an Ion Torrent S5 sequencing system, with an Ion Chef and Torrent Server, I think we've maxed our Sequencing Room.

Great interview of Dr Steve Horvath by Dr Rhonda Patrick. Betterhumans Inc. got a nice mention towards the end (1:05:28) regarding one of several collaborations we have ongoing with Dr Horvath.

Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks Consistent patterns of age-based alterations in DNA methylation can be harnessed to estimate age, serving as a sort of "clock," the premise of which is truly remarkable: Predict a person's age (or even lifespan), based on chemical modifications to their DNA that reflect the biological life history o...

We raised $14,636 in donations on Giving Tuesday, Dec 3, 2019 and finally rec'd our check today (2-21-2020) from Network for Good. Thanks to all of you, esp the Methuselah Foundation for your generosity. We're using the funds to help us purchase an Olympus CKX53 microscope with CKX-CCSW confluency checker software and the R1 Cell Counter.

Happy New Year's Eve from Betterhumans. We're all working hard today to slow aging and help defer age-related illnesses!

Dave Asprey and I talk about longevity and our recent Betterhumans antiaging clinical trials in this Bulletproof Radio podcast.

Not-So-Science Fiction: Extending Your Healthspan Gets Real – James Clement #608 A deep dive into anti-aging and longevity with James Clement, a leading research and groundbreaking developments in these areas from a particularly personal perspective.

Here's how much NAD+ levels are depleted with age. We found that typical 70-80 year old Americans had nearly undetectable plasma NAD+ levels. Among other things, NAD+ is essential to keeping DNA repaired.

Open Access paper: https://doi.org/10.1089/rej.2018.2077

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