Clancy Lab

Clancy Lab

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The Clancy Lab aims to develop and implement computational approaches to understand mechanisms of excitable disease in the heart and brain.

You can access also Clancy Lab at:

www.clancylab.com

Photos from Clancy Lab's post 12/19/2023

Festivities with Clancy and Vorobyov labs.

Toward Digital Twin Technology for Precision Pharmacology 12/14/2023

Our most recent study on digital twins:

Toward Digital Twin Technology for Precision Pharmacology The authors demonstrate the feasibility of technological innovation for personalized medicine in the context of drug-induced arrhythmia. The authors u…

09/01/2023

So psyched to share our latest work and very grateful for the commentary: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP284391

https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP285309

08/21/2023

Super excited about this collaborative work led by Pei-Chi Yang PhD: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP284391

Rate-dependent effects of state-specific sodium channel blockers in cardiac tissue: Insights from idealized models 08/21/2023

Exciting new paper out led by Steffen Docken PhD:

Rate-dependent effects of state-specific sodium channel blockers in cardiac tissue: Insights from idealized models A common side effect of pharmaceutical drugs is an increased propensity for cardiac arrhythmias. Many drugs bind to cardiac ion-channels in a state-sp…

07/28/2023
07/26/2023

Our very own Khoa Ngo representing the Clancy and Vorobyov labs at the World Congress of Pharmacology earlier this month. I'm so glad he got to meet dear friend and colleague Professor Junko Kurokawa!

A computational model predicts s*x-specific responses to calcium channel blockers in mesenteric vascular smooth muscle 06/29/2023

A new pre-print describing a new model for vascular smooth muscle and mechanisms of s*x specific hypertension - Led by Dr. Hernandez-Hernandez!

A computational model predicts s*x-specific responses to calcium channel blockers in mesenteric vascular smooth muscle The function of the smooth muscle cells lining the walls of systemic arteries and arterioles is to regulate the diameter of the vessels to control blood flow and blood pressure. Here, we describe an in silico model, which we call the “Hernandez-Hernandez model”, of electrical and Ca2+ signaling ...

Photos from Clancy Lab's post 06/29/2023

Representing at the Multiscale Modeling Meeting at NIH!

Igor Vorobyov on Twitter 03/18/2023

https://twitter.com/vorobyovucd/status/1636890027476267008?s=46&t=mfNJ5_fo2Wa_4XrS8xu87A

Igor Vorobyov on Twitter “An awesome poster presentation earlier today by Dr. Gonzalo Hernandez-Hernandez from lab in at the 8th Annual UC Davis Postdoctoral Research Symposium!”

03/08/2023

Superb visit by Leon Glass - had a huge inspirational impact on me in the very early years !!

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Department Of Physiology And Membrane Biology And Pharmacology, University Of
Davis, CA
95616