Clancy Lab
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The Clancy Lab aims to develop and implement computational approaches to understand mechanisms of excitable disease in the heart and brain.
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www.clancylab.com
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12/19/2023
Festivities with Clancy and Vorobyov labs.
12/14/2023
Our most recent study on digital twins:
Toward Digital Twin Technology for Precision Pharmacology The authors demonstrate the feasibility of technological innovation for personalized medicine in the context of drug-induced arrhythmia. The authors u…
09/01/2023
So psyched to share our latest work and very grateful for the commentary: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP284391
https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP285309
Super excited about this collaborative work led by Pei-Chi Yang PhD: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP284391
08/21/2023
Exciting new paper out led by Steffen Docken PhD:
Rate-dependent effects of state-specific sodium channel blockers in cardiac tissue: Insights from idealized models A common side effect of pharmaceutical drugs is an increased propensity for cardiac arrhythmias. Many drugs bind to cardiac ion-channels in a state-sp…
07/28/2023
07/26/2023
Our very own Khoa Ngo representing the Clancy and Vorobyov labs at the World Congress of Pharmacology earlier this month. I'm so glad he got to meet dear friend and colleague Professor Junko Kurokawa!
06/29/2023
A new pre-print describing a new model for vascular smooth muscle and mechanisms of s*x specific hypertension - Led by Dr. Hernandez-Hernandez!
A computational model predicts s*x-specific responses to calcium channel blockers in mesenteric vascular smooth muscle The function of the smooth muscle cells lining the walls of systemic arteries and arterioles is to regulate the diameter of the vessels to control blood flow and blood pressure. Here, we describe an in silico model, which we call the “Hernandez-Hernandez model”, of electrical and Ca2+ signaling ...
06/29/2023
Representing at the Multiscale Modeling Meeting at NIH!
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Department Of Physiology And Membrane Biology And Pharmacology, University Of
Davis, CA
95616
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