Precision Health Reports

Big news for anyone who orders Precision Health Reports for their patients or for themselves.

In March 2026, the ACC and AHA published the most important update to cardiovascular risk guidelines in nearly ten years. These are the standards that determine who should be on cholesterol-lowering medication, what their treatment targets should be, and which risk factors deserve serious attention.

As of May 1, 2026, every Precision Health Reports Cardiometabolic Risk Assessment fully reflects every change in this new guideline. Here are the highlights:

✅ The risk calculator that determines your 10-year heart risk has been updated to PREVENT which is a more accurate tool that accounts for kidney function and blood sugar alongside traditional risk factors. We adopted this in December 2025, before it became the standard.

✅ The threshold for "high risk" was cut in half. Patients who scored between 10–19% on the old scale and were told they were intermediate risk now formally qualify for more aggressive prevention.

✅ Women's cardiovascular risk factors are now more complete. Conditions like preeclampsia, gestational diabetes, premature menopause, and PCOS are now explicitly recognized in the guidelines and captured in our updated assessment questionnaire.

If you've ordered an Assessment recently, the report they received already reflects these updated standards.

Full details here 👇

precisionhealthreports.com

Most people show up to their doctor with a "normal, but maybe a little high" LDL-cholesterol and leave thinking they're fine.

But LDL-C is a mass measurement. It tells you how much cholesterol is riding in your LDL particles—not how many particles are carrying it.

That distinction matters. A lot.

Particle number (ApoB) predict cardiovascular events in people with metabolic dysfunction, insulin resistance, and diabetes—populations where discordance between LDL-C and ApoB is common.

When LDL-C looks normal but particle count is elevated, you're looking at residual risk that standard panels miss entirely.

Doctors who measure ApoB find what the lipid panel leaves behind.

If you don't get a Cardiometabolic Risk Assessment, at least as your primary care to measure your ApoB at your next exam.

ApoB vs LDL-C: Why Particle Count Predicts Risk Better | Precision Health Reports LDL cholesterol alone can miss hidden risk. See how ApoB particle count provides even clearer insight for heart disease prevention.

The new American College of Cardiology guidelines just came out and recommend that every adult be screened for Lipoprotein(a) just once.

1 in 5 people carry elevated Lp(a). About 3% of the population has been tested. Why? It's not often covered by insurance so most doctors are hesitant to order a ~$20-25 test.🤷‍♂️

Lipoprotein(a) is a genetically determined cardiovascular risk factor that standard cholesterol panels don't catch. It doesn't respond to diet or exercise. It requires its own test, and it changes the clinical conversation entirely.

If your physician hasn't mentioned Lp(a), ask about it at your next visit.

Precision Health Reports's Assessments include Lp(a) as part of a complete cardiometabolic picture, because risk factors this significant deserve more than a footnote.

Note: we also have Lp(a) available as a standalone test for just $22. No doctor order required. FSA/HSA eligible expense.

High Lp(a) Levels: What It Means & What You Can Do About It | Precision Health Reports High Lp(a) is largely genetic and significantly raises cardiovascular risk. Learn what causes elevated lipoprotein(a), what levels are concerning, and what treatments exist.

Insulin resistance often shows up in your labs years before a diabetes diagnosis. Insulin resistance is the key linkage between metabolic and cardiovascular health.

Most tests don't catch changes in insulin resistance early enough.

LP-IR, the lipoprotein insulin resistance score, is one of the most validated early markers available.

Here's how it compares to HOMA-IR, fasting insulin, and other common methods.

LP-IR vs. Fasting Insulin: Why LP-IR Is the More Reliable Measure | Precision Health Reports Fasting insulin is highly variable. See why the LP-IR score, derived from NMR lipoprotein patterns, is a more reliable measure of insulin resistance.

Your cholesterol panel is missing something.🧬

LDL-C tells you how much cholesterol is in your blood. LDL-P and ApoB tell you how many particles are carrying it. These particles are what cause plaque.

Two patients can have the same LDL-C and completely different cardiovascular risk. This is why there is so much confusion about whether high cholesterol matters or not.

Instead of relying on social media influencers, learn why advanced lipid testing exists.

LDL-P vs ApoB: Which Better Measures Cardiovascular Risk? | Precision Health Reports Compare LDL-P and ApoB as measures of atherogenic particle number. Learn why guidelines favor ApoB and how Precision Health Reports gives the full picture regardless of your particle number choice.

Have you ever been told your labs look "normal", but you still don't feel right?

Cardiometabolic disease is one of the most common and under-detected conditions in the US.

It's not a single diagnosis. It's a cluster of metabolic and cardiovascular conditions that share one root cause: insulin resistance.

We wrote a thorough, plain-language guide to help you understand what it is, how it develops, and what a real personal assessment looks like.

https://precisionhealthreports.com/what-is-cardiometabolic-disease

We'd love to hear your questions in the comments.⬇️

What Is Cardiometabolic Disease? — Precision Health Reports Cardiometabolic disease is not a single condition. it is a system of interconnected metabolic and cardiovascular disorders, all sharing a common root cause. Understanding that root cause changes how you measure, prevent, and treat it.

Most people only look at cholesterol (LDL-C). But cholesterol alone doesn’t tell you how many LDL particles are in your blood — and particle number (LDL-P) can reveal hidden cardiovascular risk even when cholesterol seems “normal.”

We’ve just updated our LDL-P page with clear FAQs and answers for health optimizers and anyone curious about advanced lipid testing.

Check it out here:
👉

LDL-P or ApoB vs LDL-C | Why Particle Count Reveals True Heart Risk — Precision Health Reports Learn why LDL particle number (LDL-P or ApoB) is more accurate than LDL-C for assessing heart disease risk. Discover testing options and clinical guidance.

The real cost of diabetes and heart disease in the workplace isn’t just in hospital bills.

👉 It’s in missed workdays, lower productivity, and employees leaving the workforce early.

For a company of 1,000 employees, that can mean millions of dollars each year.

There’s a better approach: preventive, biomarker-driven health programs that catch risk early and save money.

📩 HR leaders and executives — message us to learn how we can help protect both your people and your bottom line.

The Hidden Cost of Cardiometabolic Disease at Work — Precision Health Reports It’s not just medical claims. Chronic conditions drive absenteeism, presenteeism, and lost productivity. Discover how prevention saves millions. Learn how prevention reduces hidden workplace costs.

Metabolic Syndrome isn’t just a checklist of risk factors. It’s a progressive condition that silently drives heart disease and diabetes.

That’s why Precision Health Reports goes beyond “yes or no” diagnoses by using the Metabolic Syndrome Severity Score (MSSS).

This score provides a continuous, trackable measure of risk and helps patients see whether lifestyle changes are really moving the needle.

👉 Discover why MSSS changes the game for prevention:

Metabolic Syndrome and the Metabolic Syndrome Severity Score: A Precision Approach to Risk Detection — Precision Health Reports Learn how metabolic syndrome is diagnosed, why it matters, and how the Metabolic Syndrome Severity Score used by Precision Health Reports provides a more accurate, personalized view of cardiometabolic risk.

Your cholesterol test might be leaving out the most important number.

LDL cholesterol (LDL-C) only measures the amount of cholesterol inside particles. ApoB measures how many particles are in your blood. Those particles drive plaque buildup and heart disease.

It’s possible to have a “normal” LDL-C but still be at high risk because ApoB is elevated.

When these numbers differ, it may be confusing, but cardiovascular disease risk always tracks with ApoB.

We explain why this happens and why ApoB is the stronger test for protecting your heart:

👉 https://precisionhealthreports.com/apob-vs-ldl-cholesterol