Analysis Mode

🔜We are happy to announce to be the at KEYNOTION Pharma Global Bioprocessing 4.0 Summit & Exhibition
in Frankfurt

Our team is going to give a session about how to use AI cell culture profiling for improved upstream process control and modelling.

From the recent POLL we have identified the key points for our session, where we aim to:
📍Turn data into growth
📍Increase product quality and yield
📍Real-time data pre-processing
📍Help QC (Quality Control) team execute decisions quickly
📍Prediction of the CQAs (Critical Quality attributes)

"The AnalysisMode solution improves your upstream bioprocessing capacity in just 30 days." Would you like to give a try? Request a demo 👉🏼 https://lnkd.in/gRj4XgH4

Let’s meet & discuss how we can help your company reach biomanufacturing milestones faster with the power of AI👉🏼 https://lnkd.in/gT6Z9ptk

Moving to the second type of single-used bioreactors with  👉🏻 

Stirred tank bioreactors (STBRs) are single-used reactors used to culture biological agents such as cells, enzymes, or antibodies. They are contactors where the well-mixed among phases is obtained by internal mechanical agitation. The impeller in the bioreactor provide rapid agitation to disperse all compounds and achieve a homogeneous concentration inside the bioreactor. 

Thank you for the shared valuable learnings.

"The AnalysisMode solution improves your upstream bioprocessing capacity in just 30 days." Would you like to give a try? 👉🏻 https://lnkd.in/gRj4XgH4

Let’s meet and discuss how we can help your company reach biomanufacturing milestones faster 👉🏻 https://lnkd.in/gT6Z9ptk

We are continuing with at AnalysisMode

Our topic for today is about -used .

Single used Bioreactor is also a disposable bioreactor with a disposable bag instead of a culture vessel, in which the lining that is in contact with the cell culture will be plastic.

We start with the first type called which has integrated temperature sensors, load cells with filter heater that can handle cell cultures up to 25 L. Many advantages included in that bioreactor:
✍🏻 Handling is convenient and easy
✍🏻 Minimal footprint with less space
✍🏻 Sampling & harvest is easier inside the bioreactor
✍🏻 Operations can be done in single or dual culture mode
✍🏻 Reliable temperature measurement
✍🏻 Accurate weight measurement

Thank you for the shared valuable learnings.

"The AnalysisMode solution improves your upstream bioprocessing capacity in just 30 days." Would you like to give a try? 👉🏻 https://lnkd.in/gRj4XgH4

Let’s meet and discuss how we can help your company reach biomanufacturing milestones faster  👉🏻  https://lnkd.in/gT6Z9ptk

💥We are happy to be On-Site for at Testa Center to our technology in the innovation industry.

team is very thankful for this opportunity hosted by Cytiva, STUNS Life science RISE Research Institutes of Sweden, Pall Corporation revolutionizing   4.0 industry in Region Uppsala.

🛠️We kicked off our week with many valuable learnings and hands-on laboratory work with the industrial .

We would like to thank Jens Hammarlund Jozsef Vasi Jesper Hedberg Anisha Khan Magdalena Eggens and Malin Wiederholm and for their warm welcome and guidance at Testa Center

🚀We are excited for our journey in the coming 3 weeks!

& tissue regeneration is trending in the world of research.

"It's induced pluripotent stem cells–so IPS cells that everybody knows from Yamanaka sensei’s Nobel Prize. So how we unpack the biology and the genomics behind the hair follicles?"

To continue on this interesting question, you can listen to our AnalysisMode Episode with Cenk Sumen - working now as Scientific Chief Officer at MaxCyte, Inc.. This podcast was broadcasted during his previous role as Chief Technology Officer at Stemson Therapeutics in the

Many opinions were discussed generating insights about & , such topics were about:
👉Stemson's therapeutics mission in regenerating hair follicles
👉Studying to counteract the accelerated aging
👉Causes of tissue failure, aging factors and escalating longevity

Listen Now ➡️https://lnkd.in/gYk89Mra

From our recent , we identified what the scientists are looking to having in their manufacturing pipeline.

Today, we focus in our series on how to reduce batch , where selecting the most optimal platform for your product is crucial. The key consideration for is process , where there is no perfect parameter with the tremendous options available in bioprocessing.

From there AnalysisMode team try to understand your and supply guide to select optimal scale-up strategy. We ask like:

👉Is the cell expanding differently when taken from different patients?

👉Does the cell have a high demand of oxygen?

👉What type of digital algorithmic tools needed to process the scale up?

👉Is computational fluid dynamics useful to understand the bioreactor physics?

👉Is process simulation informative in studying the cell behavior?

👉How many inline and offline parameters can we correlate to improve batch quality?

👉What is the yearly amount of product that can be produced?

Check out the Blog  ➡️https://lnkd.in/gCc86Yey

As your partners, we always want to learn more about your needs & tackle your dilemmas in

Special thanks to and for their shared guidance and learnings.

          

Do you know how your cells are stored to keep their awesomeness?

about liquid nitrogen and !

💡 The best method for cultured cells is storing them in liquid nitrogen in a complete medium in the presence of a cryoprotective agent such as dimethylsulfoxide ( ).

💡 An established is a valuable resource and its replacement is expensive and time-consuming, it is vitally important that they are frozen down and preserved for long-term storage.

Learn about basics with help of Thermo Fisher Scientific guide: https://lnkd.in/dby7H7iE

📣We're proud to join Center, Cytiva, Life science , Research Institutes of Sweden, Corporation to revolutionize 4.0 industry in Region Uppsala.

Testa Challenge is start to finish Bioprocess − producing and purifying a monoclonal antibody (mAb), where its process is outlined mainly:
1️⃣Production of mAb with CHO cells using fed-batch technique in single-use bioreactor
2️⃣Clarification of the culture using depth filtration
3️⃣Purification of mAb using affinity chromatography followed by additional polishing step with multimodal chromatography resin

Our team in AnalysisMode aims to:
🔬Validate our AI CellSim technology in the biotech industry
📽️Build a brand awareness of our bioreactor software tool
⚗️Study step-by-step troubleshooting occurring in the upstream bioprocess
💾Craft an understanding of the personnel handling data from the bioreactor
⚒️Develop our technology & identifying new parameters for validation.

We are excited to embark on this journey together with ArgusEye AB, Nyctea Technologies, Scitara Corporation, and Timegate Instruments Ltd. and their innovations.

As your partners, we always want to learn more about your needs and discuss innovations ➡️https://bit.ly/3gt4ywk

We continue with another session of at AnalysisMode

📍 Today we talk about

Mammalian cell culture is the process of growing animal cells in vitro in a flask or dish. Most mammalian cells in culture can be divided into three basic categories based on their morphology:

📍 Fibroblastic (or fibroblast-like) cells are bipolar or multipolar and have elongated shapes. They grow attached to a substrate.

📍 Epithelial-like cells are polygonal in shape with more regular dimensions and grow attached to a substrate in discrete patches.

📍 Lymphoblast-like cells are spherical in shape and are usually grown in suspension without attaching to a surface.

Learn more from Thermo Fisher Scientific at: https://lnkd.in/dby7H7iE

🔆The power of education and data in is immense.

"How are you using AI to leverage inequalities between developed countries & developing countries and how can this help drive innovation as well?

”To continue on this interesting question, you can listen to our AnalysisMode Episode with Jomet John, the co-founder of & platform of Zerotoo

This time Belma , our Head of Business Development was the co-host for this episode discussing:
📍Mathematics, Research and Data Science building Zerotoo
📍Zerotoo values in education and skills development
📍Leveraging AI to teach machines human behavior

Listen Now ➡️ https://lnkd.in/dFFUMQKX

🔅Another week with new learning about 4.0.

Today, we dive into the gene therapy workflow steps
1️⃣ Plasmid Development & Production
2️⃣ Cell Expansion
3️⃣ Plasmid Transfection
4️⃣ Viral Vector Production
5️⃣ Purification
6️⃣ Quality Control & Regulation
7️⃣ Bulk Storage & Fill

❓Services❓
services specialize in , which is the first phase of the bioprocess from cell line development and cultivation to culture expansion of the cells through harvest.

❓Aim❓
We particularly aim to decrease the time from to in cell and gene therapy

❓How❓
We offer a web-based bioreactor simulating a . Empowering to run a thousand of virtual cell culture experiments – in minutes.

💡We thank Thermo Fisher Scientific & Thermo Scientific for the valuable information and guidance 🔎

Would you like to accelerate your scientists with AI?

Let's discuss the opportunities ➡️
https://bit.ly/3gt4ywk