Bioanalysis Zone

Bio-Techne and Refeyn have announced the launch of an integrated analytical workflow designed to address a persistent challenge in the development of bispecific antibodies and biosimilars. The new approach combines imaged capillary isoelectric focusing (icIEF) fractionation with mass photometry, making it possible to analyze both charge and size variations in complex biologic molecules within approximately 4 hours.

The technology aims to provide deeper insights into the therapeutic candidates while reducing the time and sample volumes required for testing.

Find out more here:

New workflow simplifies bispecific antibody and biosimilar characterization A new analytical workflow developed by Bio-Techne and Refeyn could simplify the characterization of bispecific antibodies and biosimilars.

Will Richa Pandey win your support?

Check out the finalists’ profiles and help us choose the 2026 bioanalysis rising star! 🏆 https://hubs.ly/Q04hS_xn0

⏳ Have you voted yet? Time’s ticking — listen to the four Bioanalysis Rising Star Award finalists present their cases and cast your vote for who you think should win.

Have your say now >>> https://hubs.ly/Q04hTLCN0🏆🌟

Have you read the latest Tech Note from SCIEX?

Check out ‘Low-ng/mL quantitation of GLP-1 analog in rat plasma’ to discover methods that demonstrate how optimized triple quadrupole mass spectrometry enables selective, reproducible measurement of high‑potency peptide therapeutics in complex matrices.

>>> https://hubs.ly/Q04fMsbM0

What are the biggest bioanalytical challenges in transitioning from small molecules to therapeutic oligonucleotides?

In our latest Ask the Experts feature, Basile Khara, Kevork Mekhssian and Long Yuan discuss the strategies involved in transitioning from small molecules to oligonucleotides, as well as the valuable learnings from peptide and protein bioanalysis, and where these approaches diverge.

Find out more here >>>

https://hubs.ly/Q04gM3yY0
Waters Corporation

Ask the Experts: bioanalysis of therapeutic oligonucleotides In this Ask the Experts feature with Waters Corporation, our experts investigate the bioanalysis of therapeutic oligonucleotides, diving into a broad exploration of the unique challenges, strategies and innovations involved in this specialized area of bioanalysis.

Sartorius demonstrates the benefits of the enhanced data acquisition rate on the Octet® R8e in their latest Application Note.

Download to learn more >>>https://hubs.ly/Q04hsnHc0

🌟 Four finalists. One rising star. Your choice! 🌟

Voting for the Bioanalysis Rising Star Award is LIVE! https://hubs.ly/Q04hTKwy0

These finalists represent the next generation of scientific excellence — make your vote count! 🗳️

Interested in expanding your knowledge of biomarkers? On Bioanalysis Zone’s biomarker page, you’ll find the latest trends on multi-omics integration, AI-driven analysis, expert interviews, and novel research on autoimmune diseases, like in Merck Life Science's new scientific poster.

Learn more about biomarkers today! >>> https://hubs.ly/Q04d-_0p0

𝗪𝗲𝗶𝗴𝗵𝗶𝗻𝗴 𝘂𝗽 𝘃𝗶𝗿𝗮𝗹 𝘃𝗲𝗰𝘁𝗼𝗿𝘀 𝘃𝘀 𝗟𝗡𝗣𝘀

QPS, LLC's Zamas Lam reviews the advantages and disadvantages of lipid nanoparticles and viral vectors for gene-based therapeutic delivery, including their immunogenicity risks, transduction efficiency and manufacturing considerations.

Read the full Editorial here >>>

Choosing the right delivery vehicle: navigating the trade-offs between LNPs and viral vectors In this expert option, Zamas Lam reviews the advantages and disadvantages of LNPs and viral vectors for gene-based therapeutic delivery.

A successful approach to biomarker discovery and analysis depends on multiple factors, including effective sample collection and advanced technologies for data interpretation.

In this interview, Professor Melanie Bailey shares her expert perspective on the critical role of sample collection and explains how her lab tackles biomarker discovery in translational research.

Read the full interview with Melanie here: https://hubs.ly/Q04jc6jV0

Waters Corporation

Navigating biomarker discovery in translational research Professor Melanie Bailey shares her perspective on the critical role of sample collection and explains how her lab tackles biomarker discovery in translational research.