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CELL is a biotechnology research company inspired by the CRISPR revolution overtaking the global sci
03/12/2019
We are pleased to share that on December 1st, CELL had the opportunity to give a seminar about the CRISPR Revolution at Ain Shams University, Faculty of Pharmacy as part of achieving our vision to be the bridge that connects global advanced technologies and researchers. The event was planned under the supervision of the Vice Dean for postgraduate studies and scientific research, Dr. Khaled Abu Shanab. In this seminar, we covered the CRSIPR technology and its mechanism and how this system revolutionized the world of scientific research since its discovery. We also shared some of the CRISPR applications in the biomedical field that are currently in the process of undergoing clinical trials.
We were honored by the presence of ambitious researchers and grateful to Dr. Khaled Abu Shanab for giving us the chance to talk about our services as a step in achieving our goal to a brighter future.
06/05/2019
On April the 2nd, Cell conducted the "CRISPR Revolution" seminar at City of Science Research & Technology Applications (SRTA) City.
Our team presented and discussed the background and applications of CRISPR technology. The topics covered included
• Background on CRISPR gene-editing technology
• CRISPR practical workflow
• CRISPR Bioinformatics
• Application of CRISPR technology in Agriculture, Environment and
Pharmaceutical industry/ biomedicine
We were honored by the presence of researchers from different disciplines, and an interesting discussion following the seminar!
16/12/2018
Having trouble in precisely editing tool target gene?
CELL offers you its new service by the breakthrough CRISPR technology guaranteeing high specificity & efficiency for gene modification.
Don't hesitate to contact us and ask for your design
https://cell-biosciences.com/
10/12/2018
Since its discovery few years ago, CRISPR technology has revolutionized the field of genome editing, offering high flexibility and efficiency. Emerging as a powerful gene editing tool, extensive research has been done to explore CRISPR mechanism of action and potential use across a wide range of applications, holding great promise in the future and raising many concerns as well. The CRISPR tool is made of a catalytically active endonuclease known as Cas9 that could be programmed to almost any target genomic region by a short guide RNA (sgRNA) inducing a double strand break in the target DNA. Through this tool, efficient gene knock-out/knock-in can be achieved allowing researchers to investigate a wide array of genes and explore their roles. For more information about CRISPR tool; follow this link: https://cell-biosciences.com/crispr-as-genome-editing-tool.
is a powerful tool for Genome Editing
The Future has finally arrived! Scientists can now permanently alter and edit DNA by functionally removing certain genes or adding others.
This is done using a simple yet powerful tool called CRISPR.
The applications are UNLIMITED! They range from crop modification, modifying yeasts to make biofuels and editing in mosquitos so they cannot transmit diseases such as malaria. CRISPR can also be used to treat a range of medical conditions that have a genetic component, including cancer, hepatitis B or even high cholesterol.
The CRISPR/Cas system is a prokaryotic immune system first discovered in bacteria and archeae. It establishes resistance to foreign genetic elements such as those present within plasmids and phages by inducing cuts in their genetic material.
CRISPR/Cas system is composed of an endonuclease protein called Cas enzyme responsible for introducing double stranded cuts in the DNA. In addition to a piece of short RNA sequence complementary to the target sequence, named guide RNA whose function is to guide the Cas protein to the specified DNA target sequence
Following the double strand cut, the cell starts to repair the break most commonly
through sealing the cut by joining the two ends of the DNA back together by the non homologous end joining (NHEJ) repair pathway. Since this process of DNA repair is not perfect,deletions and insertions could happen resulting in disruption of the gene. This can be useful in knocking out genes or disrupting ones with mutations. To overcome the issue of random modification, the cell could be provided by a piece of donor DNA template which is designed to be inserted within the cut region through the homology directed repair (HDR) repair pathway. This allows for more precise modifications to be done.
The video attached will show you more applications for CRISPR/Cas system.
Cell is an innovative contract-based Research & Development company, specialized in technology transfer to researchers, working in the fields of Biotechnology, molecular biology, biomedicine, and bioinformatics.
Our mission is to transfer advanced global technologies in order to develop higher impact research. Our business is based on the accumulation of advanced knowledge, which enables us to unravel the potential for creating optimal conditions for your research needs while developing innovations for the future. Cell is a bridge between the international advanced technologies, which are being used in the highly developed global research platform, and the Egyptian research community.
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