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Fresh in LabRulezGCMS Library – Week 20, 2026! 🔬📚 Explore the latest GC and GC/MS resources driving speed, confidence, and safety.

• MDCW / William & Mary: GC×GC-TOFMS for fire debris analysis optimized. Chemometrics with UMAP uncovered patterns missed by PCA; hexane and methanol emerged as preferred ILR extraction solvents. Tools: LECO corporation BTX4D with Paradigm Shift RFF, ChromaTOF Sync 2D, R. 🧪🧠
• Shimadzu: Multiresidue pesticides analysis in Annatto with GCMS-TQ8050 NX. Modified QuEChERS + GC-MS/MS deliver trace-level, reproducible quantitation in a highly pigmented matrix. LabSolutions Insight and GCMS Smart Pesticides Database Ver.2 streamline validation. 🌱🍽️🎯
• Thermo Fisher Scientific: Sentinel PRO 710 environmental mass spectrometer. Magnetic sector precision + membrane inlet enable real-time VOC monitoring down to 5 ppb; high sample-point coverage enhances worker safety. 🏭☣️📈

Our Library never stops expanding—dive in and accelerate your workflows! 🚀

×GC

News from LabRulezGCMS Library - Week 20, 2026 This week we bring you application note by Shimadzu, poster by MDCW / William & Mary and brochure by Thermo Fisher Scientific.

Quality isn’t only about instruments—it’s the whole journey from sampling to actionable reporting. Eurachem spotlights pre- and post-analytical proficiency testing (PT/EQA) to verify end-to-end performance and drive harmonisation. ISO 15189 already calls for schemes that check “the entire process.” ✅

• Why it matters 🔍: Captures errors missed by routine PT—from sample prep to interpretation—boosting consistency across labs.
• What it looks like 🧭:
• Clinical chemistry interpretation: align advice using patient context.
• Microbiology (food poisoning): choose targets, methods, and information dissemination.
• Toy testing: assess to EN 71, select clauses, tests, and labelling.
• Drinking water: report results, uncertainties, and pass/fail per Directive 98/83/EC.
• Impact 📈: Improved guidelines, stronger comparability, and more confident decisions.
• Get involved 🤝: Find PT/EQA providers via national accreditation bodies or EPTIS.

Let’s raise the bar for reliable results—before and after the measurement. 🔬📊

Pre- and post-analytical proficiency testing Discover how pre- and post-analytical PT/EQA schemes improve the quality, harmonisation, and reliability of routine laboratory analyses.

Two can’t-miss Group Discussions at the 44th ISCC & 21st GCxGC will tackle greener official methods and the future of capillary LC. 🌍🧪

• IUPAC Round Table: Greenness of official sample preparation (Wed, May 20, 13:00–14:00, Room Dolomiti) 📅📍 AGREEprep assessments show most standard methods score

Group Discussions at 44th ISCC & 21st GCxGC Discover key Group Discussions at ISCC & GCxGC 2026 covering green analytical chemistry, official methods, and the future of capillary LC adoption.

ISC 2026 brings powerhouse Tutorial Lectures to the world’s oldest separation science series! 🔬🚀 Impact spans pharma, environment, food and health across chromatography, electrophoresis, mass spectrometry, miniaturized separations and sample prep.

• Bezhan Chankvetadze — Tbilisi State University 🎓
• Martin Gilar — Waters Corporation 🧪
• Václav Kašička — Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences 🧫
• Jörg P. Kutter — University of Copenhagen 🎓
• John A. McLean — Vanderbilt University 🧬
• Peter Schoenmakers — University of Amsterdam 📘
• František Švec — Charles University 🎓

• Plus: international exhibition and vendor seminars showcasing the latest instruments and services 🤝
• Register now — Early-bird & authors’ payment deadline: May 15, 2026 📅⏳

Tutorial Lectures at ISC 2026 Discover ISC 2026 tutorial lectures presented by leading scientists in chromatography, separation science, electrophoresis, and mass spectrometry.

Volatile PFAS demand a new playbook 🔬⚙️. Daniela Cavagnino, M.S. (Thermo Fisher Scientific) shows why TD‑GC‑MS/MS underpins two complementary methods:

• ASTM D8591‑24 🧪: Targets FTOHs and neutral PFAS in chamber/ambient air. Enables product stewardship and indoor air assessments with ng/m³ sensitivity (~780 pg/m³ in 20 L). µ‑CTE studies found 8:2 FOET dominant, emission rate 0.131 ng/g/min.

• EPA OTM‑50 🏭: Verifies PFAS destruction at stationary sources, tracking VFCs like CF₄. Addresses ultra‑volatiles, high CO₂ (±30% bias check), humidity, and ppt‑level detection.

Thermo Scientific workflows:

• D8591‑24: TD100‑xr + TRACE 1610 GC + TSQ 9610, with automated IS addition, dry purge, cryogen‑free focusing, and Chromeleon CDS 📈.

• OTM‑50: Markes UNITY‑xr preconcentration, dedicated traps, ISQ 7610 or TSQ 9610 for added selectivity ✅.

One platform, distinct strategies: What do products emit? What remains after destruction? ♻️

Volatile PFAS and the Role of TD-GC-MS/MS ASTM D8591-24 and EPA OTM-50 highlight differences between volatile PFAS emissions testing and PFAS destruction verification using TD-GC-MS/MS.

🔬 GC-APCI‑MS/MS unlocks “hidden” large PAHs in pyroplastics and environmental samples. 🔥♻️

• Sensitive detection of 314–424 Da PAHs with minimal cleanup/fractionation 🧪
• Case study: 2021 M/V X‑Press Pearl spill (Pamunugama Beach, Sri Lanka) 🌊 — pyroplastics carried ≥100× higher large PAHs vs. white nurdles ⚠️
• 1,3,5‑triphenylbenzene emerges as a strong marker for burned‑plastic pollution 🎯
• Distinct large‑PAH fingerprints enable source apportionment and combustion‑temperature insights—key for environmental forensics 📈
• Implementable on conventional GC with APCI; ready for microplastic monitoring workflows 🔧

By Cara Megill, Douglas M. Stevens, Christopher M. Reddy, Bryan D. James, Robert K. Nelson, Frank L. Dorman (ACS Omega, 2026). DOI: https://doi.org/10.1021/acsomega.5c11703

GC-APCI-MS/MS Detection of Large PAHs in Pyroplastics GC-APCI-MS/MS enables sensitive detection of large PAHs as potential chemical markers of pyroplastics.

Your spectroscopy and GC/GC-MS week is here! 🔬🚀 LabRulezGCMS Week 20/2026 brings 5 must-attend webinars across Raman, FTIR, GC, and GC/MS. Dive into automation, food safety, and cutting-edge analytics.

• Thermo Fisher Scientific: Uncovering Microplastics: Identification, Quantification, and Exposure Assessment (Tu, 12.5.2026, 08:00 CEST) 🌊🧪🔎
• AZoM: From Lab to Line: Leveraging GC and Process MS for Petrochemical Gas Analysis (We, 13.5.2026, 16:00 CEST) ⛽⚙️⏱️
• Milestone: Modern Sample Prep for Organic Contaminants: PAHs, PFAS, MOSH/MOAH in Food (We, 13.5.2026, 16:00 CET) 🍽️♨️♻️
• Thermo Fisher Scientific: End-to-end automation in GC/GC-MS: Trends, tools, and practical implementation (We, 13.5.2026, 18:00 CEST) 🤖⚡📈
• GERSTEL: Automating Food Safety Workflows for the Analysis of Edible Oils and Fats (We, 13.5.2026, 20:00 CEST) 🧈✅🧪

Search and filter 5,500+ GC, LC, MS and spectroscopy webinars. Details and registration in the Webinars section at LabRulezGCMS. 🔗

Webinars LabRulezGCMS Week 20/2026 5 webinars: automation, food safety, GC-MS, microplastics, MOSH/MOAH, PAHs, petrochemical analysis, PFAS, process MS, sample preparation

Toxic legacy in our rivers 🌊⚠️ PCBs still linger. In this episode of Concentrating on Chromatography, David Oliva speaks with Francis Femi Oloy on tracking 25 PCB congeners across six rivers in southwestern Nigeria—and turning numbers into real risk.

• Why they persist: old transformers + sediment remobilization ♻️
• Method: liquid–liquid extraction (DCM/hexane), silica/alumina cleanup, rotary evaporation + N2 blowdown, GC-ECD for ultra-sensitive chlorinated detection 🧪
• QA/QC: surrogate recoveries ~85–114%, S/N-based detection limits 📈
• Insights: wet-season spikes from runoff and resuspension 🌧️
• Impact: toxic equivalency (TEQs) to communicate human/ecological risk 👥🦆

Key takeaway: Meticulous concentration makes or breaks trace PCB analysis, and GC-ECD remains a go-to for halogenated pollutants in real-world matrices.

Listen on Spotify, Apple Podcasts, or watch on YouTube 🎧📺

Tracking Toxic PCBs in River Water using GC-ECD Interview with Francais Femi Oloy on PCB monitoring in Nigerian rivers using GC-ECD, extraction workflows, cleanup, and trace analysis methods.

EU food safety is tightening under Regulation 396/2005 🇪🇺. Here’s how precise QuEChERS evaporation keeps labs compliant 🔬🍎

• What’s new: 259 audits in 2025 and a default MRL of 0.01 mg/kg raise the bar ⚖️📊
• Why it matters: Evaporation can make or break results—think analyte loss, volatility, degradation, and contamination 💨🧪
• Best practice: Nitrogen blowdown over rotary protects labile/volatile pesticides and delivers reproducible final volumes for low LOQs ✅
• Lab fit: Seamless with LC-MS/MS and GC-MS/MS workflows for broad, multi-residue coverage 🧬🧯
• Solution spotlight: Organomation’s N-EVAP—±0.5°C water bath control, individual needle flow, inert SS/PTFE pathway, 6–45 positions, and closed-system filtration to block ambient contaminants 🛡️♻️
• Compliance gains: 70–120% recoveries, LOQ ≤ 0.01 mg/kg, stronger QC, and cleaner audit trails for the European Commission 🗂️🔍

Insights from David Oliva, Organomation. Elevate your QuEChERS workflow and stay ahead.

EU Regulation 396/2005: Pesticide Residue Testing and the Critical Role of QuEChERS Evaporation in Food Safety Nitrogen concentration of QuEChERS extracts for reliable pesticide residue analysis under EU Regulation 396/2005.

🔥🌫️ Wildfire smoke is a moving chemical target. At MDCW 2026, Caleb Marx (University of Lethbridge) shows how thermal desorption coupled with GC×GC sharpens analysis of VOCs and PAHs—far beyond conventional filters. 🧪

• ⚠️ Why it matters: Filters miss gas‑phase organics; TD–GC×GC captures volatile and semi‑volatile species with solvent‑free efficiency.
• 🛠️ What’s new: Data‑driven optimization of sorbent beds (e.g., Tenax TA/Carbopack X and a triple‑bed) plus tuned conditioning and desorption.
• 📈 Key results: ~166 unique peaks per sample; 19 of 41 targets confirmed in controlled white spruce smoke, including BTEX and PAHs.
• ⏱️ Practical wins: Reduced conditioning/desorption times, 35‑day storage stability, and sorbent choices tailored to concentration (urban air vs. wildfire plumes).
• 🌍🛡️ Impact: Cleaner chromatograms, better recoveries, and a stronger foundation for health risk assessment and policy.

🎥📄 Full talk and PDF via LabRulez.

Thermal desorption GC-MS for VOCs and PAHs in smoke Explore TD–GC×GC for wildfire smoke analysis, including sorbent optimization, VOC profiling, storage stability and complex smoke characterization.

• 🚀 Fresh in the LabRulezGCMS Library (Week 19): three standout resources pushing GC/GC/MS and Raman forward! 💡

• 🧪 MDCW / JEOL: Kirk Jensen (JEOL USA) demonstrates flow‑modulated GC×GC‑QMS without flow splitting using the JEOL JMS‑Q1600GC UltraQuad directly with a SepSolve INSIGHT modulator. High carrier gas flows, rich 2D chromatograms, and robust IDs across pesticides, perfumes, and fuels—no cryogens needed; future optimization includes hydrogen. 📈

• ⛽ Shimadzu: Detailed Hydrocarbon Analysis on the Nexis GC‑2030 per ASTM D6730. PONAsolution speeds PONA/DHA identification and reporting; SH PONA Tuning Column + SH‑1 PONA deliver crisp separations across 100+ gasoline components. ⚙️

• 🔬 Thermo Fisher Scientific: Fiber‑optic‑enabled Raman with the Thermo Scientific DXR3 Flex. Analyze through glass/plastic, handle aqueous matrices (water’s weak Raman), and resolve inorganic phases—versatile, maneuverable probes with optimal 785 nm excitation. 📊

• 📚 Explore the growing repository for GC/MS and related techniques.

News from LabRulezGCMS Library - Week 19, 2026 This week we bring you application note by Shimadzu, presentation by MDCW / JEOL and technical note by Thermo Fisher Scientific!