Psychoactives MDPI

Psychoactives MDPI

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Psychoactives is an international, peer-reviewed, open access journal on psychoactive substances.

A Comparative Neurophenomenology of the Psychedelic State and Autism: Predictive Processing as a Unifying Lens 29/05/2026

Read Review "A Comparative Neurophenomenology of the Psychedelic State and Autism: Predictive Processing as a Unifying Lens" by Dr. William Roseby and Ms. Catriona Osborn Moar.

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A Comparative Neurophenomenology of the Psychedelic State and Autism: Predictive Processing as a Unifying Lens Serotonergic psychedelics, particularly psilocybin, lysergic acid diethylamide (L*D), and dimethyltryptamine (DMT), are increasingly recognised as powerful tools to advance the understanding of consciousness and its relation to brain activity. Psychedelic research has informed neuroscientific theori...

A Systematic Review of the Prevalence of Substance Abuse in the South Pacific Region 27/05/2026

Check "A Systematic Review of the Prevalence of Substance Abuse in the South Pacific Region" by Dr. Wole Akosile, Mr. Daniel McDonald, Dr. Henry Aghanwa, and Prof. Bola Ola.

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A Systematic Review of the Prevalence of Substance Abuse in the South Pacific Region Background: This review examines the prevalence of substance abuse and related disorders in South Pacific nations. Methods: The review focused on data included in reports published since 2000 from countries like Samoa, Papua New Guinea, Fiji, and French Polynesia, excluding Hawaii, New Zealand, Aust...

Cannabis, Extracts, and Individual Phytocannabinoids—All the Same or Substantially Different? A Call for Better Characterization of Cannabis Products 25/05/2026

Read the Review "Cannabis, Extracts, and Individual Phytocannabinoids—All the Same or Substantially Different? A Call for Better Characterization of Cannabis Products" by Dr. Gerhard Nahler.

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Cannabis, Extracts, and Individual Phytocannabinoids—All the Same or Substantially Different? A Call for Better Characterization of Cannabis Products Cannabis and its derivatives are increasingly popular. The public perception of “cannabis” is commonly related to abuse potential with no sharp distinction to “marijuana”, “cannabinoids”, “hemp”, and cannabis derivatives. Delta 9-tetrahydrocannabinol (THC)—rich cannabis (“marijua...

Female Drug Use in the Ethnographic Record: A Cross-Cultural Analysis of Presence, Variation, and Cultural Context 22/05/2026

Read the recently published article "Female Drug Use in the Ethnographic Record: A Cross-Cultural Analysis of Presence, Variation, and Cultural Context" by Mr. Drake Rinks and Prof. Dr. Casey J. Roulette.

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Female Drug Use in the Ethnographic Record: A Cross-Cultural Analysis of Presence, Variation, and Cultural Context Male-biased drug use is a consistent finding in contemporary epidemiology, yet most global evidence derives from urban and industrialized populations. As a result, little is known about gendered substance use in small-scale societies, leaving unresolved whether male-biased drug use reflects universa...

When Advice Becomes Infrastructure: Ethical Governance of Conversational AI in Psychoactive Substance Information Ecosystems 20/05/2026

Check recently published Opinion "When Advice Becomes Infrastructure: Ethical Governance of Conversational AI in Psychoactive Substance Information Ecosystems" by Prof. Jaewon Lee.

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When Advice Becomes Infrastructure: Ethical Governance of Conversational AI in Psychoactive Substance Information Ecosystems Public debates about psychoactive substances have traditionally been organized around the pharmacology of compounds and the institutional control of supply. In digitally mediated societies, however, the pathways through which people encounter psychoactives are increasingly informational: search engi...

18/05/2026

Check the Case Report "Mitragynine Pseudoindoxyl Withdrawal Treated with Macro-Dosed Buprenorphine Induction: A Case Report and Review of the Literature" by Dr. TaReva Warrick-Stone et al.

Link to read: https://brnw.ch/21x2A1j

Psychoactives in 2025: Consolidating an Interdisciplinary Platform for Psychoactive Substance Science and Looking to the Future 15/05/2026

We invite you to read the Editorial "Psychoactives in 2025: Consolidating an Interdisciplinary Platform for Psychoactive Substance Science and Looking to the Future" by our Editor-in-Chief Prof. Dr. Ricardo Dinis-Oliveira.

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Psychoactives in 2025: Consolidating an Interdisciplinary Platform for Psychoactive Substance Science and Looking to the Future In 2025, Psychoactives continued its clear upward trajectory, strengthening its position as an international, peer-reviewed, open-access journal dedicated to advancing the science of psychoactive substances, spanning pharmacology, clinical psychiatry, toxicology, neuroscience, forensic science, and ...

Psychedelic Use and Missed Needed Mental Health Treatment: Gender Differences in Unmet Perceived Need for Care 14/05/2026

We invite you to read the newest published paper, "Psychedelic Use and Missed Needed Mental Health Treatment: Gender Differences in Unmet Perceived Need for Care" by Dr. Sean Matthew Vina.

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Psychedelic Use and Missed Needed Mental Health Treatment: Gender Differences in Unmet Perceived Need for Care While prior research links psychedelic use to improved psychological outcomes, less is known about whether psychedelic exposure relates to engagement with formal mental health care when treatment is recognized as needed. Using publicly available, de-identified pooled data from the National Survey on...

05/05/2026

Check the newly published paper "The Incongruous Alcohol–Physical Activity Association Reexamined: Veteran and Nonveteran Outcomes" by Ms. Samantha McCowen, Mrs. Kieleha Ingram, Dr. Julie A. Partridge and Dr. Justin T. McDaniel.

Link to read: https://brnw.ch/21x2cET

Disparities in Synthetic Cannabis Use Among U.S. Adults, 2022–2024 30/04/2026

Check the new article "Disparities in Synthetic Cannabis Use Among U.S. Adults, 2022–2024" by Prof. Delvon T. Mattingly, Mr. Meman Diaby, Dr. Osayande Agbonlahor and Dr. Joy L. Hart.
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Disparities in Synthetic Cannabis Use Among U.S. Adults, 2022–2024 Synthetic cannabinoids are widely available in the United States, yet contemporary national data on who uses these products, and disparities in use, are limited. To assess disparities in lifetime and past-year synthetic cannabis use (each yes/no), we used 2022–2024 National Survey on Drug Use and ...

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