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A case report published in Frontiers in Psychiatry described the case of a teenage boy who had developmental delays and was diagnosed with ADHD, pediatric acute-onset neuropsychiatric syndrome (PANS), autoimmune encephalitis, and autism spectrum disorder at age 14. Doctors suspected that chronic Bartonella and Lyme-related (Borrelia) infections might be contributing to his symptoms, so he began long-term antimicrobial treatment at age 15 using several antibiotics over the course of his care.

According to the report, the boy experienced substantial improvements in learning, attention, behavior, and social skills during treatment. His IQ increased by seven points, his standardized reading and math scores improved, and he gained 35 pounds after his appetite returned. He transitioned from special education into a regular classroom without accommodations, remained at grade level through high school, and was later accepted into a four-year university. The authors reported improvements in several symptoms, including oppositional behavior, anger, obsessive-compulsive symptoms, mood, and tics, while noting that treatment continued because some symptoms returned when antimicrobial therapy was stopped.

PMCID: PMC10473095 PMID: 37663607

Neuroscientists show how common parasitic infection causes seizures and psychiatric illness for some Forty million Americans are infected with a parasite called Toxopla...

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