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≤. Further experimental procedures are provided in Supplementary Figures and Supplementary Tables. For chemoradiotherapy, for, for chemotherapy,. For violin plots, a line

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exact test × contingency table was used to assess the difference in distribution between the groups in ie cluster skewness. right In –, – for multiple comparisons and corrections. , ≤, ≤, ≤,

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mature-immature-monocyte-macrophages to cell-monocyte-macrophages. , percentage of cells positive for granzyme and on treatment groups and cell subpopulations. For example,

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chemoradiotherapy arm, whereas all other patients receiving other chemoradiotherapy combinations are colored green. For, each "" is a patient, denote no treatment, denote

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myeloid clusters, and "" is cells to granulocyte clusters for monocyte-macrophages. , the density of cell-helper non-regulatory cells, and the ratio of

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s immune cell types summed up by patients and each patient is a column. The treatment status of chemoradiotherapy patients is shown in black and green as shown. , the broad

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immune composition of the cluster types identified in . "" is the comparison between cluster cells and bone marrow cells "" is cluster cells neutrophils to granulocytes eosinophils are

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comparisons of – unsupervised hierarchical clustering of invasive tumor regions identified by histopathology are provided in the Supplementary Table. The input is the cell density data for

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samples. Each symbol represents an individual patient, the horizontal line represents the histopathological region type is shown in the pie chart above each stacked bar. For –, each

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neoantigens. Specifically, we designed lentiviral vectors for priming in animals that feasible receiving neoadjuvant chemotherapy, chemoradiation were site-approved with written

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immune composition of treatment groups by spatial location. , broad immune composition of spatial location as a function of treatment group. For and , the contribution of the

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"" is the total number of patients who did not receive treatment patients who received adjacent pancreas and tertiary lymphoid structures, untreated, chemotherapy, radiation,

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