European Radiology

Radiogenomics promises noninvasive tumour profiling, however the extent to which imaging morphology reflects tumour lineage versus host-organ milieu remains unclear. This study amied to quantify the relative influence of tumour type and anatomical environment on contrast-enhance CT radiomic phenotypes (Sajjad Rostami et al.)

https://link.springer.com/article/10.1186/s41747-026-00691-5

🚨 Radiological Classification of Non-Anastomotic Biliary Strictures After Liver Transplantation

Non-anastomotic biliary strictures (NAS) remain one of the most challenging biliary complications after liver transplantation, often associated with graft dysfunction and complex post-transplant management. This article proposes a radiological classification system for NAS based on imaging distribution and severity, aiming to improve standardization of reporting and facilitate clearer communication between radiologists, hepatologists, and transplant surgeons.

"A structured imaging-based classification may support more consistent assessment of biliary complications, improve comparability across centers, and contribute to optimized clinical decision-making in transplant patients. These findings highlight the growing importance of standardized radiological frameworks in complex hepatobiliary imaging and multidisciplinary transplant care. 🖥️📊" - Sonja Jankovic



https://link.springer.com/article/10.1007/s00330-026-12515-6 (Chikako Endo et al.)

Pulmonary arterial hypertension is a severe complication of systemic lupus erythematosus. Current screening methods often miss early vascular changes. This study aimed to characterise subclinical pumonary haemodynamic alterations in SLE patients without known pulmonary arterial hypertension using 4D flow CMR (Xin Chen et al.)

https://link.springer.com/article/10.1186/s41747-026-00692-4

🫁📊 CT-Based Lung Ventilation Metrics: Establishing Reference Ranges in Healthy Individuals

Quantitative CT-based ventilation analysis is emerging as a promising tool for regional assessment of pulmonary function beyond conventional spirometry. This study establishes reference ranges for CT-derived lung ventilation metrics in healthy individuals and evaluates their relationship with pulmonary function tests (PFTs), demonstrating strong correlations between CT-derived parameters and established functional measurements.

"These findings support the growing role of functional CT imaging in respiratory assessment by providing spatially resolved information on lung ventilation that cannot be captured by global pulmonary function tests alone. Establishing normative reference values represents an important step toward integrating quantitative ventilation imaging into clinical and research workflows. 🖥️🫁" Sonja Jankovic



https://link.springer.com/article/10.1007/s00330-026-12559-8 (Charlotte E. van den Berg et al.)

🧠🔬 PSMA PET: The Answer to MRI-Occult Prostate Cancer… or Another Mirage?

Multiparametric MRI (mpMRI) has transformed the diagnostic pathway for prostate cancer, yet a substantial proportion of clinically significant prostate cancers (csPCa) may still remain undetected in patients with negative or equivocal MRI findings. This commentary explores the emerging role of PSMA PET/CT as a complementary imaging modality for detecting MRI-occult disease, highlighting evidence from prospective studies such as PRIMARY and PEDAL. The authors discuss how PSMA PET may improve sensitivity and negative predictive value while potentially reducing unnecessary biopsies in selected patients with persistent clinical suspicion of prostate cancer. 🧲☢️

"At the same time, important questions remain regarding the biological significance of PSMA-positive/MRI-negative lesions, optimal patient selection, cost-effectiveness, and the risk of overdetecting clinically indolent disease. These findings reinforce the growing concept that prostate cancer imaging should move beyond single-modality assessment toward a more integrated, biology-driven diagnostic framework. 🔍" - Sonja Jankovic



https://link.springer.com/article/10.1007/s00330-026-12596-3 (Thomas Wagner et al.)

❓ How photon technology works, and will it change the way we use computed tomography? 👇

ESR Innovation in Focus: photon-counting detector CT

https://link.springer.com/article/10.1007/s00330-025-12197-6 (Victor Mergen, Hatem Alkadhi, Matthias Eberhard, Konstantin Nikolaou & Andreas M. Hötker)

Current liver T1 mapping methods present restricted liver coverage, take long acquisition times, and mostly exclude the T1 bias induced by fat and iron effects. The authors evaluated the clinical feasibility of an accelerated water T1 mapping method for fibrosis tissue assessment (Elizabeth Huaroc Moquillaza et al.)

https://link.springer.com/article/10.1186/s41747-026-00689-z

✈️ Last week saw our Albert L. Baert Editorial Fellows in Berlin for a week of on-site training with European Radiology Editor-in-Chief Prof. Bernd Hamm.

Congratulations! 👏

T1-hypointense “black hole” lesions are recognized markers of disease severity in multiple sclerosis (MS), yet their routine quantification remains limited due to the lack of reliable automated methods. This study presents a rule-based semi-automated approach for segmenting lesions on post-gadolinium T1-weighted MRI, validated across a large multicenter cohort. The method demonstrated good volumetric agreement with manual and high lesion-wise sensitivity, highlighting its potential to support quantitative assessment. 📊

"These findings emphasize the growing value of semi-automated quantitative imaging tools in neuroradiology. By providing additional information on lesion burden and disease severity, such approaches may enhance characterization of individual MS patients and improve consistency in imaging evaluation, while still requiring expert radiologist oversight for optimal clinical use. 📌" (Sonja Jankovic)



https://link.springer.com/article/10.1007/s00330-026-12577-6 (Rozemarijn M. Mattiesing et al.)