Solve MECFS Initiative

📢New Webinar!

In 2025, Simmaron Research was the second recipient of Solve’s ME/CFS Catalyst Award in support of its study, “Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection-Associated Chronic Conditions.” The study hypothesizes that mTOR inhibition through rapamycin may address observed findings of autophagy impairment and symptoms in a subset of patients with ME/CFS and other infection-associated chronic conditions and illnesses (IACCIs).

The study advances an already FDA-approved drug for reducing key symptoms of ME/CFS and Long Covid, repurposing rapamycin to reduce fatigue, orthostatic intolerance, post-exertional malaise, and sleep issues for a subset of people with ME/CFS.

In this webinar hosted by Solve M.E. President Emily Taylor, panelists Courtney Miller (Board President at Simmaron), Dr. C. Gunnar Gottschalk (Chief Executive Officer at Simmaron), and Dr. Avik Roy (Chief Scientific Officer at Simmaron) will discuss the latest learnings from the study, and their plan to conduct an NIH exploratory treatment trial based on the data.

Register today for this free webinar with the Simmaron Research team at the link below.

When: Tues. July 14, @ 3:00 pm PT / 6:00 pm ET.

https://ow.ly/bG2H50Zg3Ct

The treatments we're all waiting for start with research, and a proposed federal rule could put that research at risk.

The government has proposed new rules that would allow active research studies to be canceled at any time, even when the science is going well, and would put political appointees in charge of approving every research grant instead of scientific experts.

For families living with ME/CFS and Long COVID, this isn't abstract. Our research depends on studies that follow patients for years. When a study is canceled halfway through, everything is lost: trust in the scientific process, the data that was collected, the trained staff, and the answers patients were counting on.

The public has until July 13 to respond, and your voice is crucial. You can call your members of Congress, email them, or submit your own public comment, all from home, in just a few minutes. Here are some places to get started:

Toolkit to call & email your Members of Congress:
https://solvecfs.quorum.us/campaign/164430/

Read the full Federal Guidance:https://www.govinfo.gov/content/pkg/FR-2026-05-29/pdf/2026-10817.pdf

Instructions on how to submit a public comment:
https://solvecfs.org/how-to-submit-a-public-comment-on-the-proposed-federal-grant-rule/

A useful deep dive analysis on the federal guidance:
https://www.ropesgray.com/en/insights/alerts/2026/06/omb-proposed-revisions-to-the-uniform-guidance-key-takeaways-for-award-recipient-organizations

Please share this post. Most people have no idea this is happening, but it will impact so many of us.

Solve M.E. VP of Scientific Programs Dr. Jessica Maya and Advocacy Director Monique Wike are in San Diego this week for the 2026 BIO International Convention.

The theme this year is “Driven by Purpose,” with a focus on solving the impossible, pushing boundaries, and delivering better outcomes for patients, public health, and the world.

If you see them there, say hello!

Researchers at the University of Illinois Chicago are conducting a research study to better understand the effects of COVID-19 on exercise capacity, fatigue, physical activity, sleep, health markers in blood, and vascular health.

You may be eligible to participate if you are 18-45 years of age, have had COVID-19, and reside in or near the Chicagoland area. Contact [email protected] or (312) 996-9594 for more information!

If you’re the one paying for everyone’s everything, that can increase intensity. Get your Intensity Score from ARCHANGELS — takes 2 minutes, and you'll get matched to free resources that can help with money and anything else you're carrying right now.

https://archangelscii.me/3Qg9ydA

Our ME/CFS Catalyst Award and Ramsay Research Grant Programs wouldn’t be possible without community support. With your help, we can turn hope into real progress. Help us fund more breakthrough studies with a gift to Solve today. All gifts will be matched up to $200k through June 30!
https://solvecfs.org/donate/

Register today for a webinar hosted by our partners at BrainInflammationCollaborative, " Research Updates & Hispanic Community Impact," featuring Solve Ramsay Research Grant winner Dr. Hector Bonilla. 6/25 @ 12 pm PT.

https://zoom.us/webinar/register/WN_c9A808evQTyuISP0TGSsHw #/

Jay Bhattacharya, MD, PhD (@NIHDirector_Jay) on X

The treatments we're all waiting for start with research, and a proposed federal rule could put that research at risk.

The government has proposed new rules that would allow active research studies to be canceled at any time, even when the science is going well, and would put political appointees in charge of approving every research grant instead of scientific experts.

For families living with ME/CFS and Long COVID, this isn't abstract. Our research depends on studies that follow patients for years. When a study is canceled halfway through, everything is lost: trust in the scientific process, the data that was collected, the trained staff, and the answers patients were counting on.

The public has until July 13 to respond, and your voice is crucial. You can call your members of Congress, email them, or submit your own public comment, all from home, in just a few minutes. Here are some places to get started:

Toolkit to call & email your Members of Congress:
https://solvecfs.quorum.us/campaign/164430/

Read the full Federal Guidance:https://www.govinfo.gov/content/pkg/FR-2026-05-29/pdf/2026-10817.pdf

Instructions on how to submit a public comment:
https://solvecfs.org/how-to-submit-a-public-comment-on-the-proposed-federal-grant-rule/

A useful deep dive analysis on the federal guidance:
https://www.ropesgray.com/en/insights/alerts/2026/06/omb-proposed-revisions-to-the-uniform-guidance-key-takeaways-for-award-recipient-organizations

Please share this post - most people have no idea this is happening, but it will impact so many of us.

Watch now! View the recording of our webinar "Sequence ME & : The Search for and Long Covid Biomarkers and Subtypes," featuring the DecodeME Management Team.

https://youtu.be/v6VQ2593m-8