Cro Splendid Lab Pvt. Ltd.

Zolmitriptan Impurities

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine. Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans can be administered alone or in combination with an NSAID like naproxen, and represent the current "gold standard" for acute migraine treatment. Zolmitriptan was first approved by the FDA for sale by Zeneca under the trade name Zomig® on November 25,
1997. It is currently available in both tablet and nasal spray forms. Zolmitriptan Impurities are primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant during the manufacturing process of the Zolmitriptan. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Zolmitriptan.

All impurities will be shared with all characterization data such as 1H NMR, 13C NMR, HPLC, MS, IR, TGA.

All Impurities are in stock with us.
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Bisoprolol Impurities

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure. It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such as Carvedilol and Labetalol. It may be used alone or in combination with other drugs to manage hypertension and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity. Bisoprolol Impurities are primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant during the manufacturing process of the Bisoprolol. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bisoprolol.

All impurities will be shared with all characterization data such as 1H NMR, 13C NMR, HPLC, MS, IR, TGA.

All Impurities are in stock with us.

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Anastrozole Impurities

Anastrozole was first approved for use in the United States in 1995. Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and acne. Aromatase inhibitors, including anastrozole, have become endocrine drugs of choice in the treatment of postmenopausal breast cancer due to a more favorable efficacy and adverse effect profile as compared to earlier estrogen receptor modulators such as tamoxifen. Anastrozole Impurities are primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant during the manufacturing process of the Anastrozole. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Anastrozole.

Anastrozole Impurity A Anastrozole Impurity B
Anastrozole Impurity D Anastrozole Impurity I

All impurities will be shared with all characterization data such as 1H NMR, 13C NMR, HPLC, MS, IR, TGA.

All Impurities are in stock with us.

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Cro Splendid Lab Pvt. Ltd.

Tacrolimus Impurities

Tacrolimus (also FK-506 or Fujimycin) is an drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 transcription. Tacrolimus Impurities are primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant (a nitrosamine impurity) during the manufacturing process of the Tacrolimus. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tacrolimus.

All impurities will be shared with all characterization data such as 1H , 13C NMR, HPLC, MS , IR, TGA

All are in stock with us.

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Abhay Gandhi Pritam Gandhi Cro Splen Cro Splendid Lab Pvt. Ltd.

N-Nitroso N-Desmethyl Edoxaban Impurity 1

Edoxaban is a medication used to prevent blood clots and reduce the risk of stroke in atrial fibrillation as well as treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE). N-Nitroso N-Desmethyl Edoxaban Impurity 1 is primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant (a nitrosamine impurity) during the manufacturing process of the drug Edoxaban. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Edoxaban.


N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl) -2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido) cyclohexyl)oxalamide

CAS No: NA
Molecular Formula: C23H27ClN8O5S
Molecular Weight: 563.03

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Cro Splendid Lab Pvt. Ltd.Cro SplenAbhay GandhiPritam Gandhi

Molecule of the week by Splendid labs - N-Nitroso Trimethoprim Impurity A

Trimethoprim is an antibiotic. It's used to treat and prevent urinary tract infections (UTIs), such as cystitis. Occasionally, trimethoprim is used to treat other types of infections, such as chest infections and acne. Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary tract infections. It is structurally and chemically related to pyrimethamine, another antifolate antimicrobial used in the treatment of plasmodial infections. N-Nitroso Trimethoprim Impurity A is primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant (a nitrosamine impurity) during the manufacturing process of the drug Trimethoprim. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trimethoprim.

N-(4-Amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-2-yl)-N-methylnitrous amide

CAS No: NA
Molecular Formula: C15H19N5O4
Molecular Weight: 333.30

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Cro Splen Cro Splendid Lab Pvt. Ltd. Abhay GandhiPritam Gandhi

Bisoprolol Impurities

Bisoprolol is a cardioselectivity β1-adrenergic blocking agent used to treat high blood pressure. It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such as Carvedilol and Labetalol. It may be used alone or in combination with other drugs to manage hypertension and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity. Bisoprolol Impurities are primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant during the manufacturing process of the Bisoprolol. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bisoprolol.

All impurities will be shared with all characterization data such as 1H NMR, 13C NMR, HPLC, MS, IR, TGA.
All Impurities are in stock with us.
Kindly share your enquiries at [email protected]
, Abhay GandhiCro Splendid Lab Pvt. Ltd.Cro SplenPritam Gandhi

Anastrozole Impurities
Anastrozole was first approved for use in the United States in 1995. Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and acne. Aromatase inhibitors, including anastrozole, have become endocrine drugs of choice in the treatment of postmenopausal breast cancer due to a more favorable efficacy and adverse effect profile as compared to earlier estrogen receptor modulators such as tamoxifen. Anastrozole Impurities are primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant during the manufacturing process of the Anastrozole. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Anastrozole.
All impurities will be shared with all characterization data such as 1H NMR, 13C NMR, HPLC, MS, IR, TGA.
All Impurities are in stock with us.
, , , CRO SPLENDID LAB PVT. LTD. Abhay Gandhi
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Molecule of the week by Splendid lab - N-Nitroso N-Desmethyl Edoxaban Impurity 1

is a medication used to prevent blood clots and reduce the risk of stroke in atrial fibrillation as well as treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE). -Nitroso -Desmethyl Edoxaban 1 is primarily used as a in the pharmaceutical industry for method development and validation to detect and quantify trace levels of this potential contaminant (a nitrosamine impurity) during the manufacturing process of the drug Edoxaban. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Edoxaban.

CAS No: NA
Molecular Formula: C23H27ClN8O5S
Molecular Weight: 563.03

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