Institute of Bioinformatics, ITPL, Bangalore

Institute of Bioinformatics, ITPL, Bangalore

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The fundamental ideas presented in the works of Marvin Minsky, Roger Wolcott Sperry, Michael S. Gazzaniga, Pierre Janet, Ernest Hilgard are further developed in “Neurocluster Brain Model”.

Short reminder:
1) Marvin Minsky was one of the founding fathers of artificial intelligence and co-founder of the Massachusetts Institute of Technology’s AI laboratory.
2) Roger Wolcott Sperry is a Nobel laureate in Physiology and Medicine for his achievements in split-brain research in year 1981.
3) Michael S. Gazzaniga is the author of the term “cognitive neuroscience”, the student and colleague of Nobel laureate Roger Wolcott Sperry, with whom he carried out experiments with split-brain patients.
4) Pierre Janet is one of the founding fathers of psychology.
5) Ernest Hilgard was ranked as the 29th most cited psychologist of the 20th century (ranking was done by “A Review of General Psychology survey”, published in 2002).

Neurocluster Brain Model analyses the processes in the brain from the point of view of the computer science.
The brain is a massively parallel computing machine which means that different areas of the brain process the information independently from each other.
Neurocluster Brain Model shows how independent massively parallel information processing explains the underlying mechanism of previously unexplainable phenomena such as sleepwalking, dissociative identity disorder (a.k.a. multiple personality disorder), hypnosis, etc.

Full description is available at the address:
Neuron model RF-PSTH - A teaching tool for students, teachers and scientists of neuroscience, biophysics and biomedical engineering.
Free program is available for Android, iOS (iPhone, iPad), Windows and macOS platforms.

Currently available artificial neuron models are unable to simulate fundamentally important features of real biological neurons: 1) antagonistic receptive fields and 2) PSTH output signal of neuron to any stimulus.
Even if some neuron models try to simulate antagonistic receptive fields then they are unable to simulate PSTH output signal, and vice versa – some other models try to simulate PSTH output signal of neuron, however these models fail to explain antagonistic receptive fields of neurons. As for example, a very popular DOG (Difference Of Gaussians) model simulates antagonistic structure of the receptive field, however DOG model fails to simulate PSTH output signal of neuron. And the vast majority of artificial neural models even fail to simulate both: antagonistic receptive fields and PSTH output signal.
For the first time ever neuron model RF-PSTH is able to simulate both antagonistic receptive fields and PSTH output signal.
Neuron model RF-PSTH is based on physics of real biological neurons.

Full description is available at the address:
Be part of Bioinformatics Congress 2017 as a speaker/delegate at Paris during November 13-14, 2017.
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The Institute of Bioinformatics (IOB) established by Dr. Akhilesh Pandey, is a non-profit academic research organization located at International Tech Park in Bangalore, and is involved in cutting-edge research in genomics, proteomics and bioinformatics.

[03/24/17]   Ph.D. studentship in Bioinformatics (1 position) at Institute of Bioinformatics (IOB), Bangalore, which integrates multi-disciplinary expertise on biomarker research. The student will work on one of the following projects: Integrative analysis of high-throughput "omics" data, including next- (NGS) and third-generation sequencing, genomics, transcriptomics, proteomics identify diagnostic, predictive and prognosis biomarkers for cancer, development of novel methods to process NGS data, and construction of data bases to manage biomedical data.
Qualifications:
1. M.Sc. in Bioinformatics
2. Candidates must have expertise in Unix/Linux operating systems and shell scripting, and have experience with programming languages including Perl or Python.
3. Candidates must have secured JRF funding from CSIR-UGC, DBT and BINC
Only candidates who can relocate to Bangalore may apply.
Interested candidates should e-mail their detailed curriculum vitae to [email protected] with subject as "Ph.D. studentship - Bioinformatics".
Short listed candidates will be called for an interview.
Last Date : April 22, 2017

[01/31/17]   Ph.D. studentship in Bioinformatics (1 position) at Institute of Bioinformatics (IOB), Bangalore, which integrates multi-disciplinary expertise on biomarker research. The student will work on one of the following projects: Integrative analysis of high-throughput "omics" data, including next- (NGS) and third-generation sequencing, genomics, transcriptomics, proteomics identify diagnostic, predictive and prognosis biomarkers for cancer, development of novel methods to process NGS data, and construction of data bases to manage biomedical data.

Qualifications:

1. M.Sc. in Bioinformatics

2. Candidates must have expertise in Unix/Linux operating systems and shell scripting, and have experience with programming languages including Perl or Python.

3. Candidates must have secured JRF funding from CSIR-UGC, DBT and BINC

Only candidates who can relocate to Bangalore may apply.

Interested candidates should e-mail their detailed curriculum vitae to [email protected] with subject as "Ph.D. studentship - Bioinformatics".

Short listed candidates will be called for an interview.

Last Date : February 28, 2017

[09/19/16]   Ph.D. studentship in Cancer Biology (2 positions)

Ph.D. admissions in Cancer Biology (2 positions) at Institute of Bioinformatics (IOB), Bangalore, which integrates multi-disciplinary expertise on biomarker research. The program involves the application of state of the art technologies to investigate biomarkers for bladder cancer recurrence and progression. This includes: identifying novel biomarkers, study the molecular pathology and understanding clinical phenotypes.

Qualifications:

M.Sc. in Life Sciences
Candidates must have secured JRF funding from CSIR-UGC, DBT or BINC
Candidates with experience in cell culture, molecular biology and/or mass spectrometry are preferred. Selected JRFs will be involved in cell culture, molecular biology experiments, proteomics and cutting edge technologies including NextGen sequencing. Only candidates who can relocate to Bangalore may apply. Interested candidates should e-mail their detailed curriculum vitae to prashant at ibioinformatics dot org with subject as "Ph.D. studentship - Cancer Biology". Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

[01/14/16]   Ph.D. studentship in Cancer Biology (3 positions)

Ph.D. admissions in Cancer Biology (3 positions) at Institute of Bioinformatics (IOB), Bangalore, which integrates multi-disciplinary expertise on biomarker research. The program involves the application of state of the art technologies to investigate biomarkers for bladder cancer recurrence and progression. This includes: identifying novel biomarkers, study the molecular pathology and understanding clinical phenotypes.

Qualifications:

1. M.Sc. in Life Sciences
2. Candidates must have secured JRF funding from CSIR-UGC, DBT and BINC

Candidates with experience in cell culture, molecular biology and/or mass spectrometry are preferred. Selected JRFs will be involved in cell culture, molecular biology experiments, proteomics and cutting edge technologies including NextGen sequencing. Only candidates who can relocate to Bangalore may apply. Interested candidates should e-mail their detailed curriculum vitae to prashant at ibioinformatics dot org with subject as "Ph.D. studentship - Cancer Biology". Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

[01/04/16]   JRF and SRF positions in DBT Center of Excellence project for Malaria Research between Institute of Bioinformatics (IOB), Bangalore and National Institute of Immunology (NII), Delhi.
Institute of Bioinformatics (IOB) (http://ibioinformatics.org/) is a premier research center for Genomics, Proteomics, Metabolomics, and Computational biology. IOB has established a state-of-the-art proteomics, genomics, and metabolomics platforms that are being utilized to explore and validate candidate biomarkers in a wide array of human diseases ranging from neurological disorders and infections to cancers. Scientists at IOB are training young researchers across India in these OMICS technologies.
Dr. Prasad’s group (http://www.ibioinformatics.org/tskprasad.php) at Institute of Bioinformatics (IOB) in collaboration with Dr. Sharma’s laboratory (http://www.nii.res.in/research/pushkar-sharma) National Institute of Immunology (NII) is looking for highly motivated Junior Research Fellows (JRF; 5 positions) and Senior Research Fellows (SRF; 5 positions), to work on project entitled “Centre of Excellence on Molecular Machinery of Plasmodium”

Qualifications for JRF:
1) M.Sc. or M.Tech in any field of Life Sciences; 2) Candidates must have secured JRF funding from CSIR-UGC, DBT, BINC and DST-INSPIRE
Qualifications for SRF:
1) M.Sc. or M.Tech in any field of Life Sciences; 2) 2 years research experience and minimum 1 publication in any peer reviewed journal
Selected JRFs and SRFs will be extensively trained in sample prep and data analysis of proteomic and multi PTM experiments on Plasmodium falciparum and its interaction with human, high-resolution mass spectrometry, maintenance of HPLC and culturing of synchronized culture of Plasmodium falciparum and a number of molecular biology techniques. Fellowship amounts will be as per DBT rules and guidelines. Interested candidates needs to send their detailed CV by email to: kes[email protected] with a subject line either as “JRF in Malaria Research” or “SRF in Malaria Research”. Shortlisted candidates will be contacted within 15 days from date of application.

[10/30/15]   Ph.D. studentship in Bioinformatics (2 positions)
Qualifications:

1) M.Sc. in Bioinformatics with experience in Next generation sequencing data analysis, using bioinformatics tools, databases, understanding of the underlying algorithms and creating algorithms.
2) Candidates must have secured JRF funding from CSIR-UGC, DBT, ICMR and DST-INSPIRE

Selected JRFs will be involved in ongoing collaborative research projects between IOB and other collaborating institutes. They will be trained in cutting edge technologies including wet lab training for confirmation of NGS single nucleotide variants at the DNA and RNA level in selected cases to participate in functional confirmation. Training will also be given on interpreting and curating NGS. Only candidates who can relocate to Bangalore (ITPL) by January 30, 2016 need to apply. Interested candidates should e-mail their detailed curriculum vitae to kavita at ibioinformatics dot org with subject as "Ph.D. studentship in Bioinformatics". Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

[07/04/15]   1. Ph.D. studentship in Cancer Biology (3 positions)

Ph.D. admissions in Cancer Biology (3 positions) at Institute of Bioinformatics (IOB), Bangalore, which integrates multi-disciplinary expertise on biomarker research. The program involves the application of state of the art technologies to investigate biomarkers for bladder cancer recurrence and progression. This includes: identifying novel biomarkers, study the molecular pathology and understanding clinical phenotypes.

Qualifications:
1) M.Sc. in Life Sciences
2) Candidates must have secured JRF funding from CSIR-UGC, DBT and BINC

Candidates with experience in cell culture, molecular biology and/or mass spectrometry are preferred. Selected JRFs will be involved in cell culture, molecular biology experiments, proteomics and cutting edge technologies including NextGen sequencing. Only candidates who can relocate to Bangalore may apply. Interested candidates should e-mail their detailed curriculum vitae to careers at ibioinformatics dot org with subject as "Ph.D. studentship - Cancer Biology". Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

[03/29/15]   IOB recruiting JRFs for Ph.D. studentship positions

1. Ph.D. studentship in Mass Spectrometry based Proteomics and Metabolomics (5 positions)

Qualifications:
1) M.Sc. in any field of Life Sciences;
2) Candidates must have secured JRF funding from CSIR-UGC, DBT, ICMR and DST-INSPIRE
3) Previous experience in a molecular biology or proteomics laboratory is advantageous

Selected JRFs will be extensively trained in sample prep and data analysis of proteomic and metabolomic experiments, maintenance of HPLC and mass spectrometry for carrying out proteomic and metabolomic analysis of cancer and infectious diseases. They will be trained in cutting edge technologies in quantitative proteomics and phosphoproteomics at IOB. Only candidates who can shuttle between Bangalore and collaborating Institutes need to apply. Candidates should have the ability to work in a team. Interested candidates should e-mail their detailed curriculum vitae to careers at ibioinformatics dot org with subject as " Ph.D. studentship - Mass Spectrometry based proteomics and metabolomics’. Short listed candidates will be called for an interview. Those without any fellowship, please do not apply.

2. Ph.D. studentship in the Translational Research in Neurological Diseases (5 positions)

Qualifications:
1) M.Sc. in any field of Life Sciences;
2) Candidates must have secured JRF funding from CSIR-UGC, DBT, ICMR and DST-INSPIRE

Selected JRFs will be involved in ongoing collaborative research projects between IOB and National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore. These JRFs will be placed in IOB-NIMHANS laboratory located at Neurobiology Research Centre, NIMHANS campus. They will be trained in cutting edge technologies including NextGen sequencing and high-resolution mass spectrometry. Only candidates who can relocate to Bangalore need to apply. Interested candidates should e-mail their detailed curriculum vitae to careers at ibioinformatics dot org with subject as "Ph.D. studentship – Research in Neurological disorders.” Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

3. Ph.D. studentship in Genomics and Proteomics of Infectious diseases (3 positions)

Qualifications:
1) M.Sc. in any field of Life Sciences;
2) Candidates must have secured JRF funding from CSIR-UGC, DBT, ICMR and DST-INSPIRE

Selected JRFs will be involved in ongoing collaborative research projects of IOB on genomic and proteomic analysis to understand host-pathogen interactions involved in the pathogenesis of Mycobacterium tuberculosis, malaria and other infectious diseases. These JRFs will spend their time between IOB and a collaborating laboratory. They will be trained in cutting edge technologies including NextGen sequencing and high-resolution mass spectrometry. Only candidates who can relocate to Bangalore and willing to travel to collaborating Institutes need to apply. Interested candidates should e-mail their detailed curriculum vitae to careers at ibioinformatics dot org with subject as "Ph.D. studentship – infectious disease biology.” Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

[11/05/14]   IOB is looking for highly motivated research students, who would like to investigate on altered proteomic and metabolomic profiles of human beings during diverse disease conditions. A number of opportunities are available to carry out deeper proteomic and metabolomic profiles of specialized organs including brain and eye. Only candidates who qualified Junior Research Fellowship and would like to pursue their Ph.D. degree in the cutting –edge research areas using advanced experimental platforms are encouraged to apply.

1. Ph.D. studentship in ‘Mass Spectrometry based Proteomics and Metabolomics’ (5 positions)

Qualifications:

1) M.Sc. in any field of Life Sciences;
2) Candidates must have secured JRF funding from CSIR-UGC, DBT, ICMR and DST-INSPIRE
3) Previous experience in a molecular biology or proteomics laboratory is advantageous

Selected JRFs will be extensively trained in sample prep and data analysis of proteomic and metabolomic experiments, maintenance of HPLC and mass spectrometry for carrying out proteomic and metabolomic analysis of cancer and infectious diseases. They will be trained in cutting edge technologies in quantitative proteomics and phosphoproteomics at IOB. Only candidates who can relocate to Bangalore and shuttle between IOB and collaborating Institutes need to apply. Candidates should have the ability to work in a team. Interested candidates should e-mail their detailed curriculum vitae to careers at ibioinformatics dot org with subject as " Ph.D. studentship - Mass Spectrometry based proteomics and metabolomics’. Short listed candidates will be called for an interview. Those without any fellowship, please do not apply.

2. Ph.D. studentship in 'Translational Research in Neurological diseases' (5 positions)

Qualifications:

1) M.Sc. in any field of Life Sciences;
2) Candidates must have secured JRF funding from CSIR-UGC, DBT, ICMR and DST-INSPIRE

Selected JRFs will be involved in ongoing collaborative research projects between IOB and National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore. These JRFs will be placed in IOB-NIMHANS laboratory located at Neurobiology Research Centre, NIMHANS campus. They will be trained in cutting edge technologies including NextGen sequencing and high-resolution mass spectrometry. Only candidates who can relocate to Bangalore need to apply. Interested candidates should e-mail their detailed curriculum vitae to careers at ibioinformatics dot org with subject as "Ph.D. studentship – Research in Neurological disorders.” Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

3. Ph.D. studentship in 'Genomics and Proteomics of Mycobacterium tuberculosis' (5 positions)

Qualifications:

1) M.Sc. in any field of Life Sciences;
2) Candidates must have secured JRF funding from CSIR-UGC, DBT, ICMR and DST-INSPIRE

Selected JRFs will be involved in ongoing collaborative research projects of IOB on genomic and proteomic analysis to understand host-pathogen interactions involved in the pathogenesis of Mycobacterium tuberculosis. These JRFs will spend their time between IOB and collaborating tuberculosis laboratory. They will be trained in cutting edge technologies including NextGen sequencing and high-resolution mass spectrometry. Only candidates who can relocate to Bangalore and willing to travel to collaborating Institutes need to apply. Interested candidates should e-mail their detailed curriculum vitae to careers at ibioinformatics dot org with subject as "Ph.D. studentship – tuberculosis research” Short listed candidates will be called for an interview. Those without any fellowship please do not apply.

ndtv.com 30/05/2014

वैज्ञानिकों की बड़ी कामयाबी, लाइलाज बीमारियों से जीत की उम्मीदें बढ़ीं

The NDTV news coverage of our human proteome study done at Institute of Bioinformatics,Bangalore

ndtv.com भारत और अमेरिका के वैज्ञानिकों ने मिलकर दुनिया में पहली बार इंसानी शरीर की रचना करने वाले प्रोटीन्स का सबसे बारीक खाका तैयार करने में कामयाबी हासिल की है। इससे कई लाइलाज बीमारियों से लड़ने में जीत की उम्मीद बढ़ गई है।

ndtv.com 30/05/2014

वैज्ञानिकों की बड़ी कामयाबी, लाइलाज बीमारियों से जीत की उम्मीदें बढ़ीं

The NDTV news coverage of our human proteome study:

http://www.ndtv.com/video/player/news/scientists-map-the-proteins/323569?hphin&video-featured

ndtv.com भारत और अमेरिका के वैज्ञानिकों ने मिलकर दुनिया में पहली बार इंसानी शरीर की रचना करने वाले प्रोटीन्स का सबसे बारीक खाका तैयार करने में कामयाबी हासिल की है। इससे कई लाइलाज बीमारियों से लड़ने में जीत की उम्मीद बढ़ गई है।

natureasia.com 29/05/2014

Indian scientists lead mapping of human proteome - Nature India

Cover story of this week's Nature..
"A draft map of the human proteome"
A joint effort of Institute of Bioinformatics and Johns Hopkins University.

http://www.natureasia.com/en/nindia/article/10.1038/nindia.2014.74

natureasia.com The Human Proteome Map is an initial catalog of all of the proteins in the human body. Also identifies 193 novel proteins from regions of the genome not predicted to code for proteins so far.

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