Institute for Systems Biology

Institute for Systems Biology

The Institute for Systems Biology is a nonprofit biomedical research organization based in Seattle, Washington. It was founded in 2000 by systems biologist Leroy Hood, immunologist Alan Aderem, and protein chemist Ruedi Aebersold. ISB was established on the belief that the conventional models for exploring and funding breakthrough science have not caught up with the real potential of what is possible today. ISB serves as the ultimate environment where scientific collaboration stretches across disciplines, where our researchers have the intellectual freedom to challenge the status quo, and where grand visions for breakthroughs in human health inspire a collective drive to achieve the seemingly impossible. Our core values ensure that we always keep our focus on the big ideas that eventually will have the biggest impact on human health. Since 2000, ISB has grown to about 200 staffers, which includes 9 faculty members and laboratory groups.

2017 Undergrad Intern Showcase - Institute for Systems Biology

Our summer program provides a paid opportunity to experience research alongside experts in systems biology to students with a diversity of backgrounds and career goals. Summer 2017 brought a fresh cohort of undergraduates interested in exploring ISB’s research in the Summer Undergraduate Research Experience Program.

Times Higher Education

ISB's Dr. Sui Huang weighs in on the anonymous peer review system in this Times Higher Education opinion piece.

"While standard grant review panels sieve out proposals that fail to meet the standard of technical rigour, they are so blunt a tool that, in the process, they also kill the most innovative, visionary projects."

Read the latest treatise from Lee Hood, "P4 Medicine and Scientific Wellness: Catalyzing a Revolution in 21st Century Medicine," in ISB's annual report.

Identification of the proteins in Plasmodium vivax provide new targets for a malaria vaccine - Institute for Systems Biology

A new report in PLOS describes the results of an international collaboration led by researchers at Institute for Systems Biology and Center for Infectious Disease Research to identify proteins in the less commonly studied malaria parasite "Plasmodium vivax." Scientists from ISB and the Center for Infectious Disease Research led an international collaboration to identify proteins in the malaria parasite Plasmodium vivax. P. vivax and P. falciparum cause the majority of malaria cases, but P. vivax is far less-studied, in part because it cannot be grown in...

About the cover : Nature Biotechnology

ISB's John Earls and Allison Kudla created the cover artwork for the August issue of Nature Biotechnology. Check it out! Nature Biotechnology journal featuring biotechnology articles and science research papers of commercial interest in pharmaceutical, medical, and environmental sciences.

How Microbes Learn to Predict the Future - Institute for Systems Biology

New study on how microbes learn to predict the future. Researchers in Nitin Baliga and John Aitchison's lab at Institute for Systems Biology published new findings in Oxford Academic (Oxford University Press)'s "Genome Biology and Evolution" on adaptive prediction in yeast. Researchers at Institute for Systems Biology (ISB) designed an experiment to evolve novel adaptive prediction capability in yeast.

Institute for Systems Biology and Arivale "Pioneer 100 Study" Published

Institute for Systems Biology and Arivale “Pioneer 100 Study” Establishes Foundation for New Industry of Scientific Wellness. Now published online in Nature Biotechnology ISB and Arivale Pioneer 100 Study: Personal, dense, dynamic data clouds enable novel insights into mechanisms of wellness and disease.

Museum of Awe with Dan Goods and David Delgado

Institute for Systems Biology's annual Consilience event hosted Dan Goods & David Delgado of NASA Jet Propulsion Laboratory for an #inspiring presentation on The #MuseumofAwe. Having seen every presentation of theirs on the web, we are happy to say that ISB got a "best of" 😉. Watch at: Dan Goods and David Delgado, NASA Jet Propulsion Laboratory visual strategists, visited Institute for Systems Biology to present their work in hopes of inspi...

This is the same study we mentioned in our earlier post about the latest from The Cancer Genome Atlas Research Network. Our Shmulevich Lab contributed analysis work.

ISB Engineer Hopes to Save the Sword Ferns in Seattle's Magnificent Forest - Institute for Systems Biology

Our researchers are as dedicated outside of work as they are at the office. Senior software engineer Paul Shannon is trying to save the sword ferns. Watch the news segment linked in the post. Seattle’s Magnificent Forest at Seward Park is located within one of the nation’s most diverse neighborhoods. The 98118 zip code in southeast Seattle is home to people of all socioeconomic classes including groups of immigrants who speak more... Read More

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