National Cancer Institute

National Cancer Institute

NCI is the lead federal agency for cancer research. Connect with us here, call us at 1-800-4-CANCER, or visit us at

Mission: NCI leads, conducts, and supports cancer research across the nation to advance scientific knowledge and help all people live longer, healthier lives. For more information about NCI, visit us at Privacy:

Early data on potential approach to treat severe COVID-19

A small study of people with severe #COVID19 identified a potential approach to treat severe respiratory distress using a cancer drug. As described in an NCI Media Availability, early data from a clinical study suggest that blocking the Bruton tyrosine kinase (BTK) protein with the cancer drug acalabrutinib provided clinical benefit to a small group of patients with severe COVID-19.

A Conversation with Bríd Ryan, Ph.D., M.P.H.

An expert on health disparities in lung cancer discusses her latest research findings and the future directions of her work. Bríd Ryan, Ph.D., M.P.H., is an NIH Stadtman Investigator in the Laboratory of Human Carcinogenesis at the Center for Cancer Research. While in her home country of Ireland more than a decade ago, she became interested in gaining research experience abroad when she happened across news of a fellowsh...

Coping – New Normal

The end of cancer treatment is often a time to rejoice. Yet at the same time, it's okay to feel sad and worried. It can take time to recover. In recognition of National Cancer Survivors Day, share this article with a loved one who is adjusting to a new normal after cancer treatment. #NCSD2020 Adjusting to physical and emotional changes after cancer treatment and tips on coping with fear of recurrence.

NCCAPS: How Does COVID-19 Affect People with Cancer?

A new NCI study will help scientists answer questions about #COVID19’s impact on cancer patients and cancer’s impact on the course of COVID-19. NCI has launched the COVID-19 in Cancer Patients Study (NCCAPS), which will help scientists answer key questions about COVID-19’s impact on cancer patients and cancer’s impact on the course of COVID-19. The study is now open to adults and will later be expanded to include children.

The process by which cancer cells spread to other parts of the body is called metastasis. Here's how it happens:

Coronavirus Rumor Control |

Rumors can easily circulate during a crisis. Here are 3 things you can do to stop the spread of disinformation related to #COVID19, according to FEMA Federal Emergency Management Agency. EspañolFEMA helps the public distinguish between rumors and facts regarding the response to coronavirus (COVID-19) pandemic.

Side Effects of Immunotherapy

Immunotherapy can cause side effects, but they may vary from person to person. The ones you have and how they make you feel will depend on how healthy you are before treatment, your type of cancer, how advanced it is, the type of immunotherapy you are getting, and the dose. Immunotherapy side effects happen when the immune system that has been prompted to act against the cancer also acts against healthy cells and tissues in the body. Learn about the types of side effects that immunotherapy might cause and where to go for more information.

Sacituzumab Govitecan for Metastatic Triple-Negative Breast Cancer

Cancer News: U.S. Food and Drug Administration recently approved sacituzumab govitecan (Trodelvy) for the treatment of a particularly aggressive form of breast cancer called triple-negative #breastcancer. FDA has approved the targeted therapy sacituzumab govitecan (Trodelvy) for the treatment of triple-negative breast cancer that has spread to other parts of the body. Under the approval, patients must have already undergone at least two prior treatment regimens.

Chemotherapy and You: Support for People With Cancer

Are you or a loved one receiving chemotherapy? Chemotherapy and You is a free booklet that you can refer to throughout treatment. It includes information about side effects and ways you can care for yourself. Covers side effects that patients may have during chemotherapy and ways to manage them.

Cancer Research in the Era of COVID-19

In a recent blog post, NCI Deputy Director Dr. Dinah S. Singer wrote about NCI’s efforts to address the pandemic by pivoting some cancer research activities to focus on #COVID19. This NCI Bottom Line blog post highlights aspects of Dr. Dinah Singer’s AACR Annual Meeting presentation. She provided an overview of NCI’s efforts toward the COVID-19 crisis by pivoting the focus of some cancer research activities. She also expanded on how NCI, alongside NIH, has implemented ne...

Nutrition Facts Label Reflects Science on Diet and Health, including Cancer

We talked with a U.S. Food and Drug Administration expert about updates to the Nutrition Facts label and how they reflect new research on diet and health, including cancer. On January 1, 2020, the Food and Drug Administration (FDA) began requiring many food manufacturers to display an updated nutrition labels on their product packaging. Experts from FDA and NCI discuss the update and the research that underpins the changes that were made.

NCI’s Role in Cancer Research

Did you know NCI is the largest funder of cancer research in the world? Learn more about how the research process works. Cancer research is a vast, complex enterprise that involves researchers from many different disciplines, working across a research continuum, to produce biomedical advances. Each advance builds on the next, and each advance spurs new ideas. Learn about NCI’s role as the largest funder of cancer re...

OUT TODAY: The first National Institutes of Health (NIH)-wide, 10-year strategic plan for nutrition research.

What if we had individualized dietary recommendations that helped us decide what, when, why, and how to eat to optimize our health and quality of life? This precision nutrition approach is among the ambitious goals set out by the 2020-2030 Strategic Plan for National Institutes of Health Nutrition Research. Unveiled today, this is the first NIH-wide research plan for nutrition to accelerate nutrition science and uncover the role of human nutrition in improving public health and reducing disease.

Exercise and Survival for Women with Breast Cancer

Getting regular exercise may increase how long some women with breast cancer live, new research suggests. Women with breast cancer at high risk for recurrence who engaged in regular exercise before their cancer diagnosis and after treatment were less likely to have their cancer return or to die compared with women who were inactive, a recent study found.

Less toxic treatment effective for adult Burkitt lymphoma

For adults with Burkitt lymphoma, an alternative treatment regimen is highly effective and less toxic than standard dose-intensive chemotherapy, a new NCI study finds. In an NCI study, an alternative chemotherapy regimen called dose-adjusted EPOCH-R that is less toxic than standard dose-intensive chemotherapy was found to be highly effective for adults with Burkitt lymphoma across all age groups and independent of HIV status.

Tests that examine the urine and bladder are used to help find and diagnose bladder cancer. Learn more about screening for these types of cancer. #BladderCancerAware

NCI COVID-19 in Cancer Patients Study (NCCAPS)

How does #COVID19 affect people with cancer? NCI plans to find out. NCI COVID-19 in Cancer Patients Study (NCCAPS) is a natural history study of COVID-19 in people who are getting treatment for cancer.

Pop-Up Testing Lab Shows Volunteer Spirit Against Deadly Pandemic

Researchers around the country have created pop-up #COVID19 testing labs to help fight the #pandemic, the National Institutes of Health (NIH) Director writes on his blog. On March 19, 2020, California became the first U. S. state to issue a stay-at-home order to halt the spread of SARS-CoV-2, the virus that causes COVID-19. The order shuttered research labs around t…

Have questions about cancer and #coronavirus? Chat with an NCI information specialist via LiveHelp: #COVID19

FDA Approves Encorafenib for Colorectal Cancer

FDA approves a new drug for some people with metastatic #colorectalcancer. The Food and Drug Administration (FDA) has approved encorafenib (Braftovi) for the treatment of some patients with colorectal cancer. The approval covers using encorafenib in combination with cetuximab (Erbitux) in adults with metastatic colorectal cancer whose tumors have a mutation in the BRAF gen...

Clinical Trials Information for Patients and Caregivers

Today is Clinical Trials Day, a great opportunity to learn more about NCI-supported programs. Note that we are monitoring NCI-supported clinical trials to address the needs of investigators and to maintain continuity of care for patients during COVID-19. Explains clinical trials, including what they are, why they are important, things to think about when deciding to take part, and questions to ask your doctor.

NCI and National Institute of Allergy and Infectious Diseases (NIAID) want your input on research approaches and priorities related to the novel #coronavirus. The Serological Sciences Network is intended to work collaboratively to expand national testing capacity as quickly as possible and to develop new tests: #COVID19

PSMA PET-CT Accurately Detects Prostate Cancer Spread

For some men with #prostatecancer, a new imaging approach may be more effective at detecting the spread of the disease than standard imaging approaches, a large clinical trial suggests. For men with localized prostate cancer at high risk of spreading, results from a large clinical trial show an imaging method known as PSMA PET-CT is more likely to detect metastatic tumors than the standard imaging approach used in many countries.

NCI Dictionary of Cancer Terms

Pop Quiz: What is it called when cancer cells are found in the body, but the place where the cells first started growing cannot be determined?

Answer: Cancer of unknown primary origin. Also called carcinoma of unknown primary and CUP. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.

[05/15/20]   The most common types of cancer in the United States include breast, lung, and prostate cancers. Learn more about the estimated numbers of new cases and deaths for each common cancer type:

Bladder Cancer Treatment (PDQ®)–Patient Version

The most common risk factor for #bladdercancer in the United States is cigarette smoking. Read more about risk factors for this type of cancer. Treatment of bladder cancer depends on the stage of the cancer. Treatment options include different types of surgery (transurethral resection, radical and partial cystectomy, and urinary diversion), radiation therapy, chemotherapy, and immunotherapy. Learn more about how bladder cancer is treated.

Did you miss our Facebook live event on how young patients and their families can cope during #COVID19? Watch the recording:

Caregivers of Cancer Patients

As a caregiver for a loved one with cancer, you may feel that there's no time left for yourself. But caring for your own needs, hopes, and desires can give you the strength you need to carry on. Being a caregiver of cancer patients can be stressful. Find out what to expect and how to deal with caring for a loved one with cancer.

NCI Part of Effort to Evaluate Coronavirus Antibody Tests

Our institute is helping validate antibody tests for the novel coronavirus. “NCI has unique research capabilities and capacities," said NCI Director Ned Sharpless. "So, to help in this public health crisis, we believe, is a moral obligation.” #COVID19 NCI scientists are helping to evaluate commercially available antibody tests for SARS-CoV-2, the coronavirus that causes COVID-19. Their work is being done with experts from several other government agencies and academic medical centers, as part of a collaborative effort to assist FDA with test vali...

Symptoms of Cancer

Often, cancer does not cause pain, so don't wait to feel pain before seeing a doctor. Here are some symptoms that cancer may cause: Cancer can cause different symptoms, such as abnormal bumps, night sweats, or unexplained weight gain or loss. Only a doctor can tell if symptoms are caused by cancer or some other problem.

Risk Factors: Sunlight

Exposure to UV radiation from the sun, sunlamps, and tanning booths causes damage that can lead to #skincancer. Learn about what you can do to protect damage to your skin. Exposure to UV radiation from the sun, sunlamps, and tanning booths causes early aging and skin damage that can lead to skin cancer. Find information, including tips, on how to protect your skin.

Advice from the Brain Tumor Community

If you are newly diagnosed or living with a brain tumor, it can be hard to find valuable support and resources. To help survivors and caregivers cope, others in the brain tumor community share their advice. #BTAM To help guide you through your brain tumor journey, patients, caregivers, doctors, and advocates share their advice.

Testicular Cancer Screening (PDQ®)–Patient Version

Did you know? There is no standard or routine screening test for testicular cancer. Learn more about how screening tests for this type of cancer are being studied in clinical trials. Testicular cancer screening has not been shown to decrease the chance of dying from the disease. It is usually found by men themselves or during a regular physical exam. Learn more about testicular cancer screening in this expert-reviewed summary.

Managing Anxiety and Distress in Cancer Survivors

Studies have shown that anxiety and stress are common among long-term cancer survivors, but research supported by NCI is exploring new ways to support the psychological and emotional health needs of cancer survivors. Many cancer survivors experience distress and anxiety long after completing treatment. Researchers are exploring ways to support the psychological and emotional needs of a diverse range of cancer survivors and how to tailor existing approaches to meet the needs of specific individuals or groups.

NCI Aims to Boost CAR T-Cell Therapy Clinical Trials

NCI will manufacture CAR T-cell therapies for clinical trials being conducted at multiple hospitals. NCI is developing the capability to produce cellular therapies, like CAR T cells, to be tested in cancer clinical trials at multiple hospital sites. Few laboratories and centers have the capability to make CAR T cells, which has limited the ability to test them more broadly.

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Videos (show all)

Questions 2 - NCI Facebook Watch Party
Questions 3 - NCI Facebook Watch Party
Cancer Health Disparities: Did You Know?
Talking Through Colorectal Cancer Prevention and Screening
Cancer and Other Illnesses during COVID-19: How young patients and families can cope
Should You Join a Clinical Trial?
What are questions to ask your doctor about your treatment?
What are questions to ask your doctor about your diagnosis?
relaxation video
Beyond Treatment: Caring for the Needs of Children with Cancer
CCDI for Twitter
Don't Fry Day - Prevention





National Institutes Of Health (NIH) Campus
Bethesda, MD

General information

The National Cancer Institute ( NCI) is the U.S. government’s lead agency for cancer research and is part of the National Institutes of Health (NIH). We welcome your opinion – whether you are a patient, family member, health professional, researcher, or simply an interested member of the public. Reporter and bloggers, please check out our Office of Media Relations on Facebook at By commenting on this page you agree to follow NCI's Comment Policy. Comments that do not adhere to this policy may be hidden or removed. Policy:

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