Janelia Research Campus, Ashburn, VA Video September 26, 2019, 3:21pm

Videos by Janelia Research Campus in Ashburn. Janelia is a pioneering research center where scientists from many disciplines gather to collaborate on some of science's most challenging problems.

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A new imaging method follows young neurons in a developing zebrafish as they travel across the embryo and organize themselves into circuits. Read the latest work from Philipp Keller’s lab, published today in Cell. https://www.janelia.org/news/how-neural-circuits-form-in-a-developing-embryo

Other Janelia Research Campus videos

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Presenting: The most complete map yet of the fruit fly brain. Janelia’s FlyEM team has traced the paths of some 25,000 neurons in the fruit fly brain and pinpointed the places where they connect. Now, all the data is available online for free. https://www.janelia.org/news/unveiling-the-biggest-and-most-detailed-map-of-the-fly-brain-yet

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A new microscopy technique is revealing cells’ fine structure in new detail. The method, developed by Eric Betzig, Harald Hess + colleagues, combines 3D super-resolution fluorescence microscopy and electron microscopy in whole cells. Published today, in Science! https://www.janelia.org/news/new-microscopy-technique-shows-cells-3-d-ultrastructure-in-new-detail

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A new imaging method follows young neurons in a developing zebrafish as they travel across the embryo and organize themselves into circuits. Read the latest work from Philipp Keller’s lab, published today in Cell. https://www.janelia.org/news/how-neural-circuits-form-in-a-developing-embryo

Happy #FourthofJuly to everyone in the United States! John Heddleston from Janelia’s Advanced Imaging Center captured these fireworks on the lattice light sheet microscope alongside AIC visitor Andy Moore. Video: dividing cells (actin and mitochondria are stained, color map: red, white, and blue).

Janelia scientists come from diverse backgrounds—We have biologists, chemists, physicists, engineers, and computer scientists who work together to solve biological problems. Who is eligible for the opportunity to lead a new research area at Janelia? Zari Zavala-Ruiz has the details. https://www.janelia.org/our-research/competition/opportunity

We’re asking applicants who submit proposals to our new research area competition to describe their leadership and mentoring philosophies. Senior Group Leader Jennifer Lippincott-Schwartz explains why that’s an important part of the application. https://www.janelia.org/our-research/competition/opportunity

“We've made tremendous strides in systems neuroscience, understanding the relationship between neural circuits and behavior, and we're going to keep doing that at Janelia, but we want to leverage the model that we've put in place here to make discoveries in other areas as well.” –Nelson Spruston on the Janelia new research area competition and why Janelia is an effective place to do science. https://www.janelia.org/our-research/competition/opportunity

If the dots in the video look like they’re flowing in opposite directions, you’re experiencing the “reverse phi” illusion. In “phi” motion, bright points appear to move right as they disappear and reappear to the right of their previous position. But when the points switch from bright to dark as they shift rightward, our brains see them “moving” to the left: this is “reverse phi.” Now, Janelia scientist James Fitzgerald, Yale University’s Damon Clark, and their colleagues have uncovered how visual neurons in fruit flies process this illusion. Two parallel pathways in the brain respond to either light or dark moving edges. The reverse-phi effect, like many real-world visual scenes, involves both light and dark stimuli. If the pathways segregate light from dark, the researchers asked, where in the flies’ visual system do these interacting signals combine to create a sense of motion? Neurons called T4 and T5 cells react selectively to either light or dark moving edges. Scientists had thought that each of these cell types could respond only to light or dark stimuli. But the new results reveal that both cell types actually process a mix of light and dark signals, the team reported December 3, 2018, in the journal, Current Biology. By tracing the source of the motion illusion to the very earliest motion-detecting neurons in the fly’s visual system, the researchers showed that this light-dark mixing is a fundamental feature of the visual processing pathway. https://www.janelia.org/news/tracing-the-origins-of-an-optical-illusion

New Microscope Offers 4-D Look at Embryonic Development in Living Mice
How do you go from a single cell to an embryo? A team of scientists from the Keller lab here at Janelia are giving researchers the first view of early organ development inside a live mouse embryo. Learn more: http://bit.ly/2CcewzE

Janelia New Research Area Competition
The Howard Hughes Medical Institute is hosting a competition to decide the next research area at Janelia. Do you have a big idea that could move science forward? www.janelia.org/new-research-area

shrimplike_crustacean from release
This stunning video of the developing embryo of a crustacean is the result of work by Janelia’s Anastasios Pavlopoulos and colleagues who harnessed the power of a multi-view light-sheet microscope to trace and study cells of the animal’s growing limbs. The study subject, Parhyale hawaiensis, is a shrimp-like marine crustacean that develops a remarkable suite of specialized limbs along its body. http://bit.ly/2HwZR1O Credit: C. Wolff et al./eLife 2018 doi: 10.7554/eLife.34410

MouseLight Demonstration
Using a high-tech light microscope to view individual neurons, Janelia scientists have created the most detailed view of the mouse brain yet. The work lets researchers follow neurons’ winding paths in 3-D. The dataset of 300 neurons is free to download and browse.

Behavior Anatomy Mapping
Learn how Janelia Group Leader Kristin Branson and colleagues created the most comprehensive neural maps of fruit fly behavior thus far. In addition to mapping different groups of neurons to behaviors, the team also identified something entirely new: the nerve cells linked to female chase behavior.

Feature Detection in Drosophilia
The brain of the fly Drosophila melanogaster processes sensory features in parallel. New research from the Card lab uncovers how select visual features are integrated by a downstream descending neuron to bias which escape maneuver a fly executes when a predator approaches.

The 9th Annual SEA-PHAGES Symposium
The 9th Annual SEA-PHAGES Symposium is the largest gathering of researchers ever hosted at Janelia! Two hundred undergraduate biology students and over 100 faculty from more than 100 colleges & universities! The SEA-PHAGES program provides faculty with the opportunity to lead a course-based research experience for primarily first-year undergraduates and gives students the opportunity to learn about bacteriophages and annotate gene sequences. Learn more: http://buff.ly/2rM9ofO #SEAsymp2017

Compass Movement
Compass nerve cells in the spherical ellipsoid body (purple) get information about turns from a different groups of nerve cells in a handlebar-shaped structure perched above the compass. Some of those cells, called P-EN neurons, detect left turns (orange), while others detect right turns (blue). After a turn, P-EN neurons help shift the needle formed by active compass neurons (red) to the left or right. Video from http://bit.ly/2rakSdN

Discover Janelia
We believe scientists can go further together than alone. Explore our collaborative culture: https://goo.gl/emdnBf #ScienceForward

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